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Estella Tembe Fokunang

Publications (7)

Preclinical In vivo Acute Toxicity Testing of Hyrdoethanolic Extracts of Ficus thonningii Blume (Moraceae) on Wistar Rat Models

Estella Tembe Fokunang, Ngo Biyiha Marilyn Orlane Ara, Ambassa Pantaleon, Njinkio Nono Borgia Legrand, Ngameni Bathelemy & Fokunang Charles · Journal of Complementary and Alternative Medical Research · 2023

Ficus thonningii (Blume) is a medicinal plant whose biological activity has been demonstrated in the management of peptic ulcers. Unfortunately, little scientific data exists on its toxicity. This is why we studied the acute and subacute oral toxicity profile of the hydro-ethanol...

Open access Research Article 10.9734/jocamr/2023/v21i3438

Phytochemical Characterization and Systemic Exposure of Bioactive Metabolites of the Aqueous Extracts of Ficus thonningii Blume (Moraceae) on Albino Wistar Rats

Estella Tembe Fokunang, Ngo Biyiha Marilyn Orlane Ara, Ambassa Pantaleon, Njinkio Nono Borgia Legrand, Ngameni Bathelemy & Fokunang Charles · European Journal of Medicinal Plants · 2023

Ficus thonningii (Blume) is considered as a herbal plant with well documented biological activity in the management of several diseases in the tropics. However, there is a gap of information on its safety and proof of efficacy in evidence-based medicine. The objective of this stu...

Open access Research Article 10.9734/ejmp/2023/v34i41131

Overview of the Advancement in the Drug Discovery and Contribution in the Drug Development Process

Estella Tembe Fokunang & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The drug discovery and development of a new chemical entity from original idea to the regulatory approval for launch into the market is a very long and complex journey. The process is complex and can take between 10-15 years, with a significant financial implication of cost of ab...

Open access Research Article 10.9734/jamps/2022/v24i10580

Pharmacovigilance of Natural Herbal Medicines Research for Efficacy, Safety and Quality Assurance of Phytomedicine Products

Estella Tembe Fokunang, Dobgima John Fonmboh, Rose Ngono Mballa, Andrew Banin Nyuyki, Lovet Benyella Fokunang, Nubia Kaba, Thérèse Bwemba Abong, Ralf Duerr, Ejoh Richard, Marie-Thérèse Abena Ondoua & Charles Ntungwen Fokunang · Journal of Complementary and Alternative Medical Research · 2020

Improved traditional medicine/phytomedicine formulations have gained a global acceptability and popularity as therapeutic agents for many diseases in Sub-Saharan Africa. Herbal products are generally considered as safe, environmentally friendly and increasingly consumed by the co...

Open access Research Article 10.9734/jocamr/2020/v12i130198

Phytochemical Screening of Ageratum conyzoides L. (Asteraceae) Aerial Parts

Ngo Biyiha Marilyn Orlane Ara, Estella Tembe Fokunang, Tabi Yves Omgba, Njinkio Nono Borgia Legrand & Fokunang Charles Ntungwen · South Asian Research Journal of Natural Products · 2024

Introduction: Ageratum conyzoides L. (Family Asteraceae) is an annual herb with a long history of traditional medicinal use in the tropical and sub-tropical region of the world. The present study was designed to screen out the major groups of phytochemicals found in the aerial pa...

Open access Research Article

Knowledge, Attitudes and Practices on Exposure to Camphor & Eucalyptus Essential Oils and Risk of Seizure Disorder in Children: A Cross Sectional Study

Marie Victoria Eyog Nkolo, Mbassi, Awah Hubert Desire, Estella Tembe Fokunang & Charles Ntungwen Fokunang · Journal of Complementary and Alternative Medical Research · 2024

Background: Camphor and eucalyptus essential oils contain camphor and eucalyptol respectively which serve as active ingredients in over-the-counter drugs to manage upper respiratory tract infections and pain in children.  However, because of their pro-convulsant properties, seizu...

Open access Research Article 10.9734/jocamr/2024/v25i2519

Ethopharmacological Approach, in vivo Antidiarrhoeic Properties of Aqueous Leaf Extract of Mallotus oppositifolium (Euphorbiaceae) and Isolation of Antidiarrheal Compound

Roger Zintchem, Gaëtan Olivier Fankem, Joseph Ngakou Mukam, Antoine Kada Sanda, Estella Tembe Fokunang, Borgia Njinkio, Paul Aimé Noubissi, Pascal Sonna, Charles Fokunang & René Kamgang · European Journal of Medicinal Plants · 2023

Mallotus oppositifolium. Müll. Arg (Euphorbiaceae) is commonly used in the Center Region of Cameroon against diarrheal syndromes and joint pains. In order to provide a scientific basis for its use in the traditional treatment of diarrhea, we proposed to evaluate the effects of aq...

Open access Research Article 10.9734/ejmp/2023/v34i71145