Background: Malaria during pregnancy remains a major public health challenge in sub-Saharan Africa and is associated with maternal anemia, adverse fetal outcomes, and immune alterations. Changes in leukocyte distribution reflect host immune responses and may provide insight into...
Open access
Research Article10.9734/ijrrgy/2026/v9i1159
Background: Pregnancy induces coordinated hematologic adaptations to sustain maternal–fetal oxygen exchange. While clinical assessment traditionally relies on red cell indices such as hemoglobin concentration, hematocrit, and mean corpuscular volume, these static measures incompl...
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Research Article10.9734/ijr2h/2026/v9i1216
Background: Sickle cell disease (SCD) is classically defined by a single-point mutation in the β-globin gene leading to hemoglobin S polymerization and erythrocyte sickling. However, accumulating evidence indicates that SCD is a complex multisystem disorder characterized by chron...
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Research Article10.9734/ijr2h/2026/v9i1212
Obesity is a chronic disease which has spread all over the world and threatens public global health. Eighty (80) obese individuals based on age groups. The table above show no significant difference in PCV (p=0.241), WBC (p=0.445), LYM (p=0.531), GRAN (p=0.514), MID (p=0.930), LY...
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Research Article10.9734/jpri/2022/v34i12A35546
Background: The global prevalence of obesity has been on the increase over the years constituting a major public health crisis. Aim: The study was done to evaluate the haematological parameters of obese and non obese individuals at Omisanjana area of Ado Ekiti, Ekiti State. Niger...
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Research Article10.9734/jpri/2022/v34i4B35401
Emmanuel I. Obeagu, Gideon Ojochegbe Amedu, Ijeoma L. Okoroiwu, Chukwum J. Okafor, Ohikhuare Okun, Ogochukwu M. T. Barbara Ochiabuto & Chukwulete Okafor Ukeekwe·Journal of Pharmaceutical Research International·2021
To determine the levels of interleukin 6 (IL-6) and iron status of football players in Madonna University, Elele, Rivers State, Nigeria. A total number of 100 subjects were recruited for the study, comprising of 50 of football players before playing football (25 males and 25 fem...
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Research Article10.9734/jpri/2021/v33i59B34393
Emmanuel I. Obeagu, Quratulain Babar, C. C. N. Vincent, Chikwendu Lawrence Udenze, Richard I. Eze, Chukwum J. Okafor, Bart I. Ifionu, Augustine Amaeze Amaeze & Florence Ngozi Amaeze·Journal of Pharmaceutical Research International·2021
For women, the most dominant type of cancer is breast cancer and perhaps one of the most recognizedreasons of death. This is a disorder of many distinct traits, many of which are known as positive hormone receptor, human epidermal receptor-2 (HER2+), and three negative breast can...
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Research Article10.9734/jpri/2021/v33i56A33889
Emmanuel I. Obeagu, Precious Omotunde, Getrude Uzoma Obeagu, Richard I. Eze, Ukamaka Edward, Chukwum J. Okafor, C. C. N. Vincent, Ejike Felix Chukwurah & Blessing Oluchi Akalonu·Journal of Pharmaceutical Research International·2021
Background: Obesity is a serious health problem, it increases heart-related diseases and its prevalence continues to increase due to genetic and lifestyle influences. This study aims to evaluate the hematological parameters of obese individuals based on gender in the Omisanjana r...
Open access
Research Article10.9734/jpri/2021/v33i43A32500
Emmanuel I. Obeagu, Quratulain Babar, Immaculata Ogochukwu Uduchi, Adaobi Maryann Ibekwe, Udunma Olive Chijioke, Chukwum J. Okafor & C. C. N. Vincent·Journal of Pharmaceutical Research International·2021
Recipients' immune systems are triggered by blood and blood component therapy. Transfusion-related immunomodulation (TRIM) is a complicated immunological response to transfusion that results in immunosuppression. The mechanisms of TRIM include the presence of residual white blood...
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Research Article10.9734/jpri/2021/v33i42A32394
Emmanuel I. Obeagu, Quratulain Babar, C. C. N. Vincent, Chukwum J. Okafor, Richard Eze, Udunma Olive Chijioke, Adaobi Maryann Ibekwe & Immaculata Ogochukwu Uduchi·Journal of Pharmaceutical Research International·2021
Severe Acute Respiratory Syndrome Coronavirus 2 is a new type of coronavirus that can cause Coronavirus Disease 2019 (Covid-19) and is associated with an increased risk of thrombosis-related pulmonary embolism. Globally, doctors have revised their management strategies for suspec...
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Research Article10.9734/jpri/2021/v33i42A32388
Adaobi Maryann Ibekwe, Emmanuel I. Obeagu, Chisom Evelyn Ibekwe, Chinonye Onyekwuo, Chioma Vivian Ibekwe, Amarachukwu Doris Okoro & Chioma Blessing Ifezue·Journal of Pharmaceutical Research International·2022
This research work seeks to investigate the challenges of exclusive breastfeeding among working class mothers in Nnamdi Azikiwe University Teaching Hospital Nnewi Anambra State Nigeria. The objective of the present study is to investigate the attitude of working mothers to exclus...
Open access
Research Article10.9734/jpri/2022/v34i46A36371
Psychoactive substance use among Secondary School Students has become an increasing public health problem in many countries. This study assessed the prevalence and patterns of psychoactive substance use among senior secondary school students of community secondary school, Umuna....
Open access
Research Article10.9734/jpri/2021/v33i57A33969
The research is set out to determine the adherence to antiretroviral therapy among HIVAIDS in Federal Medical Clinic Owerri. The purpose of the study was to assess patients knowledge of benefits of Highly Active antiretroviral Regimen, determine level of adherence among the HIV p...
Open access
Research Article10.9734/jpri/2021/v33i57A34007
Quratulain Babar, Emmanuel I. Obeagu, Chikwendu Lawrence Udenze, Bart I. Ifionu, C. C. N. Vincent, Chukwum J. Okafor, Emmanuel Ikechukwu Nwobodo & C. O. C. Ibe·Journal of Pharmaceutical Research International·2021
Synovial sarcomas are a heterogeneous group of tumors, accounting for 1-2% of adult cancers worldwide. Formation of synovial sarcoma after tissue and nerve injury, radiations induced neuropathies and latent metastasis is those events which are still controversial and need more re...
Open access
Research Article10.9734/jpri/2021/v33i54A33726
Despite the dangers associated with the increased use of codeine drugs, limited researches have addressed the specific effects of emzolyn codeine on the lung. The aim of this study was to assess the histological effects of emzolyn codeine cough syrup on the lung of Wistar rats an...
Open access
Research Article10.9734/jpri/2021/v33i49B33359
This article deals with the dynamics of the innate and adaptive immune response to severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection. SARSCoV2 is the viral factor that causes the current global coronavirus pandemic disease 2019 (COVID2019). In terms of person-t...
Open access
Research Article10.9734/jpri/2021/v33i45A32708
This study was aimed at evaluating the serum levels of Calcium, Inorganic phosphate and Magnesium together with the Body Mass Index (BMI) in lactating mothers in Owerri. A total of sixty subjects were recruited. Thirty were lactating subjects while thirty were apparently healthy...
Open access
Research Article10.9734/jpri/2021/v33i41B32360
I. L. Okoroiwu, Emmanuel I. Obeagu, Lilian Nneka Egbuobi, Adaobi Maryann Ibekwe, C. C. N. Vincent, Bright Chukwuebuka Unaeze, Calista Ndidi Adike, Udunma Olive Chijioke, Chukwuma J. Okafor, Ayomide Olusiji Soremi, Ejike Felix Chukwurah, Bart I. Ifionu & Confidence Ogechi Anyanwu·Journal of Pharmaceutical Research International·2021
The values of factor VIII (FVIII) and factor IX (FIX) were evaluated among some primary school children in Owerri zone Imo State. The aim was to assess deficiency state or reduction in activity among these children. A total of two hundred and ten (210) venous blood samples were c...
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Research Article10.9734/jpri/2021/v33i34B31864
Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, Valerie Esame Ugochi, C.C.N. Vincent, Chukwuma J. Okafor, Ejike Felix Chukwurah, Bright Chukwuebuka Unaeze, Chukwudi Ofodile Amaechi, Chetachi Blessing Okwuanaso, Ufuoma Chukwuani & Bart I. Ifionu·Journal of Pharmaceutical Research International·2021
Diabetes mellitus (DM) is a metabolic disease in which there are high blood sugar levels. Type 2 is due to the cells of the body not responding properly to the insulin produced. The aim of this study was to evaluate the enzyme activity in glutathione peroxidase in type 2 diabetic...
Open access
Research Article10.9734/jpri/2021/v33i30B31655
Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, C. C. N. Vincent, Ejike Felix Chukwurah, Chukwuma J. Okafor, Adaobi Maryann Ibekwe, Calista Ndidi Adike, Ufuoma Chukwuani & Bart I. Ifionu·Journal of Pharmaceutical Research International·2021
This study was carried out to evaluate catalase and manganese in type 2 diabetes mellitus patients. A total of 40 subjects Were included in this study. This comprised of equal number of male and female subjects respectively. Enzyme linked immunosorbent assay (ELISA) method was us...
Open access
Research Article10.9734/jpri/2021/v33i30B31638
Richard Eze, Emmanuel I. Obeagu, Arvin Nwakulite, I. L. Okoroiwu, C. C. N. Vincent, Chukwuma J. Okafor, Ejike Felix Chukwurah, Udunma Olive Chijioke & Chukwudi Ofodile Amaechi·Journal of Pharmaceutical Research International·2021
Copper is an essential trace mineral (micronutrient) that is naturally present in some foods and is available as a dietary supplement. Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.This study was desiged to assay the co...
Open access
Research Article10.9734/jpri/2021/v33i30A31616
Richard Eze, Emmanuel I. Obeagu, Arvin Nwakulite, C.C.N. Vincent, Sylvester Ogbonna Ogbodo, Adaobi Maryann Ibekwe, Chukwuma J. Okafor & Ejike Felix Chukwurah·Journal of Pharmaceutical Research International·2021
Haemoglobin genotype variants, ABO and Rh blood groups are known to vary from one population to another. Standard electrophoretic and haemagglutination techniques were employed in testing the blood samples. Of the 150 test subjects screened, HbAA in the male subjects were 58(48....
Open access
Research Article10.9734/jpri/2021/v33i29B31600
Background: High malaria burden has led to the increase use of insecticides in the tropics and subtropics. This study thus aimed at assessing the effect of insecticides inhalation on haemorrheological parameters using experimental animal model. Materials and Methods: Sixteen adul...
Preeclampsia is a serious and life-threatening pregnancy complication. In this study, the levels of inflammatory cytokines were measured in preeclamptic women in Owerri, Imo State. A total of 120 pregnant women aged 18-45 years at 20-40 weeks of pregnancy were recruited; 60 were...
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Research Article10.9734/jpri/2021/v33i42A32384
Chekwube Catherine Agu, C. N. Onwasigwe, Emmanuel I. Obeagu, C. C. N. Vincent, Udunma Olive Chijioke, Calista Ndidi Adike, Chukwum J. Okafor, Adaobi Maryann Ibekwe, Lizzy Agunwah & Confidence Ogechi Anyanwu·Journal of Pharmaceutical Research International·2021
Background: Immunization is the process by which a person’s immune system is fortified and made resistant to an infectious disease/ agent. Immunization saves millions of lives. It is the most important means of preventing childhood morbidity and mortality. This study investigated...
Open access
Research Article10.9734/jpri/2021/v33i39B32174
Background: Diabetes mellitus (DM), a metabolic disorder characterized by an excessive increase in blood glucose levels when poorly managed, has been associated with functional and structural changes in the haemoglobin molecule, cytoplasmic viscosity, and osmotic disturbances wit...
Open access
Research Article10.9734/ijtdh/2025/v46i61661
Mycoplasma pneumoniae is an organism that belongs to the family mycoplasmataceae. Its role as a disease causing agent continues to draw interest especially with the advent of highly sensitive detection techniques. This bacterium poses a health problem to both animals and humans r...
Open access
Research Article10.9734/jpri/2021/v33i55A33829
Stomach ulceration study was carried on 25 groups (5 rats each of the groups), groups (E, E1, E2, , E3 and EC, placed on 24 hours fasting before the single dose of intra peritoneal dose administration of 5ml/kg body weight of 99% ethanol and after one hour, received daily extrac...
Open access
Research Article10.9734/jpri/2021/v33i47A33000
Infertility is a serious issue disturbing reproductive ages in all society now and calling for solution for continuity. Infertility were induced on groups of animals with separate sexes; M, M1, M2 and M3; F, F1, F2 andF3 with daily subcutaneous administration of 20 mg/kg body wei...
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Research Article10.9734/jpri/2021/v33i46B32942
Chukwum J. Okafor, Bart I. Ifionu, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan·Journal of Cancer and Tumor International·2025
Introduction: Prostatic diseases, including prostate cancer (CAP) and benign prostatic hyperplasia (BPH), are prevalent pathologies in ageing men. While prostate-specific antigen (PSA) is a well-established diagnostic marker, the role of serum testosterone in distinguishing betwe...
Open access
Research Article10.9734/jcti/2025/v15i4328
Bart I. Ifionu, Chukwum J. Okafor, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan·Journal of Cancer and Tumor International·2025
Background: Vitamin A and D are both fat-soluble vitamins that are crucial for maintaining overall health and are highly indispensable, despite their minimal daily requirements. Their involvement in cell proliferation, differentiation, and apoptosis has linked them to the develop...
Open access
Research Article10.9734/jcti/2025/v15i3311
Diabetes mellitus is associated with neutered metabolism and higher Energy Expenditure. This study aimed on the use of Adenosine diphosphate (ADP), Flavin adenine dinucleotide (FAD), AcetylCo-enzyme A (ACA) and Nicotinamide Adenine Dinucleotide (NADH) as an index of energy utiliz...
Open access
Research Article10.9734/jpri/2021/v33i47B33120
Uchenna Modestus Ezugwu, Chinedum Charles Onyenekwe, Nkiruka Rose Ukibe, Joseph Eberendu Ahaneku, Christian Ejike Onah, Emmanuel I. Obeagu, Paul Isaac Emeje, Joseph Chimezie Awalu & Gabriel Ejike Igbokwe·Journal of Pharmaceutical Research International·2021
Human immunodeficiency virus (HIV) is associated with altered metabolism and increased energy expenditure, this energy requirement increases significantly as the HIV disease progresses. This study aimed on the use of Adenosine triphosphate (ATP), Guanosine triphosphate (GTP), Ade...
Open access
Research Article10.9734/jpri/2021/v33i47A32992
Chukwuma J. Okafor, Said A. Yusuf, Salma A. Mahmoud, Salum S. Salum, Sonia C. Vargas, Adu E. Mathew, Emmanuel I. Obeagu, Husna K. Shaib, Hashima A. Iddi, Masoud S. Moh’d & Warda S. Abdulrahman·Journal of Pharmaceutical Research International·2021
Diabetes type 2 (T2D) had caused the loss of millions of lives all over the world. About 50% of the patients with T2D die because of cardiovascular disease (CVD), primarily myocardial infarction and stroke. Many of the leading risk factors for CVD coexist and act synergistically...
Open access
Research Article10.9734/jpri/2021/v33i29B31591
Rodolfo Isidro Bosch Bayard, Kenechukwu M. Okafor, Chukwum J. Okafor, Diane Millo Martin, Othman Said Abdalla, Lorena Bosch Orihuela, Aniuska Palacios Noa & Emmanuel I. Obeagu·International Neuropsychiatric Disease Journal·2025
Introduction: Mental illness imposes a significant global health burden, often compounded by stigma that hinders care. Medical students, as future healthcare providers, play a crucial role in shaping perceptions of mental health and service delivery. Understanding their attitudes...
Open access
Research Article10.9734/indj/2025/v22i5516
Rodolfo Isidro Bosch Bayard, Kenechukwu M. Okafor, Chukwum J. Okafor, Diane Millo Martin, Othman Said Abdalla, Lorena Bosch Orihuela, Aniuska Palacios Noa & Emmanuel I. Obeagu·International Neuropsychiatric Disease Journal·2025
Introduction: Mental illness poses a significant global health burden. Medical students, as future healthcare providers, play a crucial role in mental health service delivery, making their knowledge and attitudes toward mental illness essential for improving healthcare outcomes....
Open access
Research Article10.9734/indj/2025/v22i4508