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Elias Adikwu

Publications (4)

Safety Assessment of Artemether/Lumefantrine/ Tinidazole on the Kidneys of Healthy and Diseased Mice

Elias Adikwu & Udeme Owunari Georgewill · Asian Journal of Biology · 2021

Artemether/lumefantrine/tinidazole- (A/L/T) can be use for the treatment of malaria; therefore its safety assessment is imperative. This study assessed its safety on the kidneys of healthy and diseased mice. Fifty four Swiss albino mice were used for this study. Mice were disease...

Open access Research Article 10.9734/ajob/2021/v11i430150

Liver Profile of Artemether-lumefantrine-tinidazole in Healthy and Parasitized Mice

Elias Adikwu & Udeme Owunari Georgewill · Asian Journal of Medicine and Health · 2021

Artemether/lumefantrine/tinidazole (A/L/T) has shown additive antiplasmodial activity; therefore its safety assessment is imperative. This study examined its hepatotoxic effect on healthy and diseased mice. Fifty four Swiss albino mice of n=6 were used. The mice were diseased wit...

Open access Research Article 10.9734/ajmah/2021/v19i330314

In-vivo Antiplasmodial Activity of Sulfadoxine/Pyrimethamine/Doxycycline on Plasmodium berghei Infected Mice

Udeme Owunari Georgewill & Elias Adikwu · Journal of Advances in Biology & Biotechnology · 2021

The search for newer antimalarial drug combinations is on the front burner due to rising Plasmodium resistance to some currently used antimalarial drugs. This study examined the antiplasmodial activity of sulfadoxine/pyrimethamine/doxycycline (S/P/D) on mice infected with Plasmod...

Open access Research Article 10.9734/jabb/2021/v24i530212

In-vivo Antiplasmodial Effect of Dihydroartemisinin-Piperaquine-Nitrofurantoin on Plasmodium berghei- Infected Mice

Udeme O. Georgewill, Festus Azibanigha Joseph & Elias Adikwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2021

Nitrofurantoin (NT) used for the treatment of urinary tract infections may have antiplasmodial activity. Dihydroartemisinin-piperaquine (DP) is an artemisinin based combination therapy used for the treatment of malaria. This study evaluated the antiplasmodial effect of dihydroart...

Open access Research Article 10.9734/jamps/2021/v23i930256