Oral and maxillofacial cancers (OMC) remain a significant global public health concern due to their high incidence, mortality rates, and long-term morbidity. Key risk factors, including tobacco use, alcohol consumption, betel quid chewing, and human papillomavirus (HPV) infection...
Open access
Research Article10.9734/aorj/2024/v7i195
Two severe and challenging-to-treat side effects of head and neck cancer (HNC) oncological treatments are osteoradionecrosis of the jaws (ORNJ) and medication-related osteonecrosis of the jaws (MRONJ). In both cases, the bone loses vitality and develops in an area that cannot hea...
Open access
Research Article10.9734/jcti/2023/v13i1229
With 500,000 new cases diagnosed each year, head and neck cancers (HNC) are among the most prevalent cancers in the world. The most effective organ-sparing therapy for patients with locally advanced HNC is concurrent chemoradiotherapy (C-CRT). Many HNC patients lose multiple teet...
Open access
Research Article10.9734/ajrimps/2023/v12i1205
A significant contributor to cancer-related morbidity and mortality worldwide is head and neck cancer (HNC). Depending on the affected site, its etiology may include risk factors like geographic differences, genetic predisposition, gender, age, type of diet, smoking and/or alcoho...
Open access
Research Article10.9734/jammr/2022/v34i234872
Radiation therapy is the most common cause of cancer-related trismus. Radiation therapy can lead to fibrosis and hypoxia in the temporomandibular joint ligaments, synovial fluid, and masticatory muscles. This makes it difficult for patients to move their jaws and eventually leads...
Open access
Research Article10.9734/jammr/2022/v34i2231599
One of the most serious and debilitating complications of radiation therapy (RT) for patients with head and neck cancer (HNC) is osteoradionecrosis of the jaws (ORNJ). ORNJ is defined as radiation-induced ischemic bone necrosis with soft tissue necrosis in the absence of primary...
Open access
Research Article10.9734/jammr/2022/v34i2131522
Head and neck cancers (HNC) account for 10–15% of all cancers globally. Curative radiation therapy (RT) and concurrent chemoradiotherapy (CCRT) with or without surgery are widely accepted standard treatment modalities for these patients. Radiation-induced fibrosis is one of the s...
Open access
Research Article10.9734/acri/2022/v22i530288
Osteoradionecrosis of the jaws (ORNJ) is a severe radiotherapy (RT) complication that occurs in 2% to 22% of individuals with head and neck cancers (HNC) who are treated with RT or concurrent chemo-RT. The accurate diagnosis of ORNJ is crucial for appropriate and prompt managemen...
Open access
Research Article10.9734/jcti/2022/v12i430187