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Edmund O. Ezirim

Publications (10)

Consumption of Potash Distorted Female Sex Hormones Which May Result in Gynaecological and Obstetrics Complaints

Edmund O. Ezirim, Emmanuel O. Ogbuagu, Christian O. Onyemereze, Emmanuel M. Akwuruoha, Isaiah O. Abali & Augustine I. Airaodion · Asian Research Journal of Gynaecology and Obstetrics · 2023

Objective: Potash is a common food additive in African particularly Nigeria. This study sought to investigate its effects on female sex hormones in Wistar rats. Materials and Methods: Locally sourced potash from Owerri, Imo State, Nigeria, was administered to 30 healthy female Wi...

Open access Research Article

Factors Influencing Family Planning Services among Rural Women in Nigeria

Edmund O. Ezirim, Oluwaseun R. Omole, Emmanuel M. Akwuruoha, Patricia I. Ejikem & Augustine I. Airaodion · International Journal of Research and Reports in Gynaecology · 2023

Aim: This study aimed to investigate factors influencing family planning services among rural women in Nigeria. Methodology: This study employed a cross-sectional, descriptive, and analytical research design to examine the factors that influence the use of family planning service...

Open access Research Article

Pathogenesis and Factors Influencing Premature Ovarian Insufficiency among Nigerian Women

Emmanuel M. Akwuruoha, Edmund O. Ezirim, Chyke I. Amah, Christian O. Onyemereze & A. I. Airaodion · International Journal of Research and Reports in Gynaecology · 2025

Background: Premature ovarian insufficiency (POI) is a significant cause of infertility and hypoestrogenic symptoms in women under 40 years, with profound reproductive, endocrine, and psychosocial implications. Limited epidemiological data exist on its pathogenesis and risk deter...

Open access Research Article 10.9734/ijrrgy/2025/v8i1132

Awareness and Level of Usage of Intermittent Preventive Treatment for Malaria among Pregnant Women Attending Antenatal Clinics in Rural Communities in Abia State, Nigeria

Emmanuel M. Akwuruoha, Edmund O. Ezirim, Christian O. Onyemereze, Isaiah O. Abali & A. I. Airaodion · International Journal of Research and Reports in Gynaecology · 2025

Background: Malaria in pregnancy (MiP) is a major public health concern in sub-Saharan Africa, contributing to maternal and neonatal morbidity and mortality. Intermittent Preventive Treatment in pregnancy using Sulphadoxine-Pyrimethamine (IPTp-SP) is a key strategy endorsed by th...

Open access Research Article 10.9734/ijrrgy/2025/v8i1121

Implication of Nephropathy in Sickle Cell Anaemia

Chika L. Uche, Edmund O. Ezirim, Abali O. Isaiah & Augustine I. Airaodion · International Journal of Advances in Nephrology Research · 2022

Aim: This study sought to investigate the effect of sickle cell anemia on kidney using endogenous biomarkers. Methodology: This study is a case-control study which enrolled 60 sickle cell anemia patients (30 males and 30 females) in a stable state at the Obafemi Awolowo Universit...

Open access Research Article

Sickle Cell Anemia Contributes to Liver Abnormality

Chika L. Uche, Abali O. Isaiah, Edmund O. Ezirim & Augustine I. Airaodion · International Journal of Research and Reports in Hematology · 2022

Aim: This study sought to investigate the implication of sickle cell anemia on hepatic biomarkers. Methodology: This is a case-control study which enrolled 60 sickle cell anemia patients (30 males and 30 females) in a stable state at the Obafemi Awolowo University Teaching Hospit...

Open access Research Article

Ethanolic Extract of Xylopia aethiopica (African Negro Pepper) Fruit Adversely Perturbed Semen Qualities in Male Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · International Journal of Research and Reports in Gynaecology · 2022

Aim: This study was designed to assess the effect of Xylopia aethiopica fruit on the sperm qualities of male Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanolic as solvent. The median lethal dose (LD50) of t...

Open access Research Article

Xylopia aethiopica Fruit Increased Prothrombin Time, Activated Partial Thromboplastin Time and Erythrocyte Sedimentation Rate of Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Prince C. Unekwe & Ifeoma N. Nweke · International Journal of Research and Reports in Hematology · 2022

Background: Traditionally, the use of Xylopia aethiopica fruit for therapeutic purposes is on the increase without any consideration of its safety and toxicity. Aim: This study was therefore designed to examine its effect on coagulation factors of Wistar rats. Methodology: The fr...

Open access Research Article

Alterations in Female Reproductive Hormones of Wistar Rats Sequel to the Administration of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Research Journal of Gynaecology and Obstetrics · 2022

Aim: This present study was designed to examine the impact of Xylopia aethiopica fruit on the reproductive hormones of female Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanol as solvent. The lethal dose of...

Open access Research Article

Effect of Ethanol Extract of Xylopia aethiopica Fruit on Oxidative Stress Indices of Wistar Rats

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Journal of Immunology · 2022

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without caution of its toxicity. Aim: This present study tends to assess its effect on the oxidative stress biomarkers of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dr...

Open access Research Article