E. L. Neo

KRAS Mutation is a Local Tumour Event and Not a Field Change in Pancreatobiliary Tumours

M. D. Chandrasegaram, D. Y. Chen, C. P. Tan, E. L. Neo, P. M. Dolan, J. W. Chen, M. E. Brooke-Smith, G. Cheetham, A. Ruszkiewicz & C. S. Worthley · Journal of Advances in Medicine and Medical Research · 2013

Background: KRAS mutation (KRM) is the earliest, most common mutation in pancreatic cancer. Accurate assessment of tumour KRM status in pancreatobiiary tumours is relevant in an era of targeted molecular therapies. Aim: To assess KRM in tumour and non-tumourous margin tissue in p...