E. G. Fakola

Design, Synthesis and Biological Evaluation and Molecular Docking Study of (Z)-7-Nitro-1-Phenyl-3-((2-((1-Phenylethylidene) Amino) Ethyl) Amino) Quinoxalin-2(1H)-One Derivatives

F. O. Taiwo, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & Craig A. Obafemi · Journal of Pharmaceutical Research International · 2026

Aims: To synthesize  (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-one derivatives and evaluate their possible biological properties. Methods: The substituted (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-o...

Open access Research Article 10.9734/jpri/2026/v38i97867

Synthesis of (Z)-2-((2-(Benzylideneamino)ethyl)Amino)-3-Methylquinoxaline-6-Sulfonyl Azide Derivatives and Their Acetylcholinesterase and Butyryl Cholinesterase Inhibitory Activities

Taiwo, F. O, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & C. A. Obafemi · Journal of Applied Life Sciences International · 2026

Aims: This study synthesized  a series of (Z)-2-((2-(benzylideneamino)ethyl)amino)-3-methylquinoxaline-6-sulfonyl azide derivatives and evaluated their inhibitory activities against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Methods: The derivatives were prepar...

Open access Research Article 10.9734/jalsi/2026/v29i5800

Design, Synthesis and Biological Evaluation of (Z)-N,N-dibenzyl-3-oxo-2-((2-((1 phenylethylidene) amino)ethyl)amino)-3,4-dihydroquinoxaline-6-sulfonamide Derivatives

F. O. Taiwo, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & C. A. Obafemi · Current Journal of Applied Science and Technology · 2026

Aims: The aim is to synthesize a range of chemical derivatives and thoroughly evaluate their potential biological activities. This process will involve designing and executing synthetic pathways to obtain the desired compounds, followed by in-depth biological assays to assess pro...

Open access Research Article 10.9734/cjast/2026/v45i94756

Design, Synthesis and Molecular Docking Study Evaluation of Acetylcholinesterase and Butyrylcholinesterase Inhibition Potential of 8-bromo-4-(2-(phenylethylidene)hydrazinyl)tetrazolo[1,5-a]quinoxaline Derivatives

F. O. Taiwo, I. J. Olawuni, O. B. Omoyeni, E. G. Fakola & C. A. Obafemi · Annual Research & Review in Biology · 2026

Aims: The aim of this study was to synthesize 8-bromo-4-(2-(1-phenylethylidene)hydrazinyl)tetrazolo[1,5-a]quinoxaline derivatives and assess their acetylcholinesterase and butyrylcholinesterase inhibitory potential. Methods: The 8-bromo-4-(2-(1-phenylethylidene) hydrazinyl)tetraz...

Open access Research Article 10.9734/arrb/2026/v41i92446