Discovery of 5-Chlorobenzimidazole-based as Promising Inhibitors of Chloroquine-Resistant Plasmodium Strains: Synthesis, Biological Evaluation, Molecular Docking and Computational Studies
Jean Paul N’Guessan, Songuigama Coulibaly, Abdulrahim A. Alzain, Drissa Sissouma, William Yavo & Mahama Ouattara · Journal of Pharmaceutical Research International · 2021
Background: To overcome drug resistance to current antimalarial drugs, we propose the synthesis and in vitro evaluation of the antiplasmodial activity of a series of 5-chlorobenzimidazolyl-chalcones against chloroquino sensitive (CQ-S) and chloroquino resistant (CQ-R) strains of...
Open access
Research Article
10.9734/jpri/2021/v33i46B32925