Diego Quiroga

Influence of MW Irradiation on the Reaction Between (2R,7R,11S,16S)-1,8,10,17-tetraazapentacyclo[8.8.1.1.8,170.2,70.11,16]icosane and p-Substituted Phenols

Diego Quiroga, Jaime Ríos-Motta & Augusto Rivera · Organics · 2025

4,4′-substituted-2,2′-((hexahydro-1H-benzo[d]imidazole-1,3(2H)-diyl)bis(methylene))bisphenols (1a–d) and 2,6-bis{[3-(2-hydroxy-5-substitutedbenzyl)octahydro-1H-benzimidazol-1-yl]methyl}-4-substitutedphenols (2a–b) were synthesized via microwave (MW) irradiation of aminal (2R,7R,1...

Open access Research Article 10.3390/org6040044

Synthesis of Antifungal Heterocycle-Containing Mannich Bases: A Comprehensive Review

Diego Quiroga & Ericsson Coy-Barrera · Organics · 2023

Mannich bases are a class of organic compounds usually obtained by the condensation reaction between an amine, a compound with active hydrogens, and an aldehyde. They are versatile intermediates in organic synthesis, and those compounds containing this motif find applications in...

Open access Research Article 10.3390/org4040035

Linear Stepwise Synthesis of 2-(Naphthalen-1-yl)-2,3,5,6-tetrahydro-1H-isoquinolino[8,1,2-hij]quinazoline: A Novel Fused Heteroaromatic Framework

Augusto Rivera, Álvaro Castillo, Jaime Ríos-Motta & Diego Quiroga · Organics · 2026

In the present work, we describe the synthesis of a new heterocyclic derivative, 2-(naphthalen-1-yl)-2,3,5,6-tetrahydro-1H-isoquinolino[8,1,2-hij]quinazoline 1, using the reaction between the aminal 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane 2 (TATD) and 1-naphthylamine 3 as th...

Open access Research Article 10.3390/org7010012