Synthesis, Antifungal Evaluation, and Structure–activity Relationship of Chlorinated Imidazopyridinyl- phenylpropenone Derivatives against Aspergillus fumigatus
Deto Ursul Jean-Paul N’guessan, Songuigama Coulibaly, Avi Tanguy Kouao, Alain A. Kacou, Kpongbo Etienne Angora, Fabrice Koffi, Ismaila Diallo & Mahama Ouattara · Chemical Science International Journal · 2025
Background: Aspergillus fumigatus is the leading causative agent of invasive aspergillosis, a deadly opportunistic fungal infection in immunocompromised patients. The increasing emergence of azole-resistant strains necessitates the urgent development of new antifungal molecules....