Daniel Lotanna Ajaghaku, Chibueze Peter Ihekwereme & Paul Chinwuba·Asian Journal of Biology·2025
This study investigated the effects of supplementation with a phenol-rich fraction of Musanga cecropioides (PRF-MC) on malaria and primaquine (PQ)-induced oxidative stress inSwiss albino mice. Plasmodium berghei infected mice were treated with PQ alone (0.25 mg/kg) and in combina...
Open access
Research Article10.9734/ajob/2025/v21i8544
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by cognitive decline, memory impairment, and oxidative stress. Aim: This study investigated the neuroprotective effects of the butanol fraction of Zapoteca portoricensis root (BFZP) in...
Open access
Research Article10.9734/ajorrin/2026/v9i1193
Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Celestine Obiora Ugwu, Detu Martins Ikpechukwu, Kingsley Chidiebere Ndu & Linus Odinakachukwu Nsude·International Journal of Pathogen Research·2025
Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits to the host. Their impact on drug bioavailability and efficacy, particularly in gastrointestinal disorders, has gained considerable interest. This paper explores how probiotics...
Open access
Research Article10.9734/ijpr/2025/v14i3367
Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Levi Onyebuchi Idokoja, Detu Martins Ikpechukwu & Damian Chukwunonso Mbah·International Neuropsychiatric Disease Journal·2025
Schizophrenia is a disorder characterized by a multifaceted pathogenic mechanism impacted by numerous genes. The investigation of its pathophysiology is mostly dominated by the dopamine hypothesis. Multi-target therapies represent a viable strategy for addressing polygenic disor...
Open access
Research Article10.9734/indj/2025/v22i4492
Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by progressive dementia, neuroinflammation, and the accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. Oxidative stress and cholinergic dysfunction are key con...
Open access
Research Article10.9734/ijr2h/2026/v9i2244
The acute and sub-chronic toxicities of the leaf extract of Newbouldia laevis, an ethnomedicinal herb use in the management of diabetes mellitus was investigated. For the acute toxicity study, 10 – 5000 mg/kg of the extract were administered orally to mice and obvious signs of to...
Open access
Research Article10.9734/jocamr/2023/v21i4443
Christian Ejike Onah, Samuel Chukwuemeka Meludu, Chudi Emmanuel Dioka, Anaelechi Jude Onuegbu, Chinwemma Florence Onah, Daniel Lotanna Ajaghaku, John Kennedy Nnodim & Obi Ejeatuluchukwu·European Journal of Medicinal Plants·2016
This study was designed to evaluate the effect of Moringa oleifera (MO) against lead acetate induced changes in some liver and kidney function parameters and oxidative stress markers in rats. Thirty six acclimatized Wistar rats were divided into six groups of six rats each (group...
Open access
Research Article10.9734/EJMP/2016/23763