Dalia S. Shaker

Comparative Studies on Dissolution and Bioavailability of Tamoxifen Citrate Loaded Binary and Ternary Solid Dispersions

Dalia S. Shaker, Mohamed K. Ghorab & Mohamed S. Teiama · Journal of Pharmaceutical Research International · 2013

Aims: This study focused on comparing binary and ternary solid dispersions (SD's) of water-insoluble Tamoxifen citrate (TMC) regarding drug dissolution and oral bioavailability. Basically, the enhanced dissolution of this drug by water-soluble polymer has not yet been reported in...

Open access Research Article 10.9734/BJPR/2014/6072

In Vitro and In Vivo Evaluation of Combined Time and pH- Dependent Oral Colonic Targeted Prednisolone Microspheres

Fahima M. Hashem, Dalia S. Shaker, Mohamed Nasr & Reem Ragaey · Journal of Pharmaceutical Research International · 2013

Aims: to enhance the anti-inflammatory effect as well as oral absorption of prednisolone (PR), through formulation of colonic targeted microspheres prepared from a blend of time and pH- dependent polymers and loaded with PR. Study Design: In Vitro and In Vivo Evaluation of Combin...

Open access Research Article 10.9734/BJPR/2013/3195