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Craig A. Obafemi

Publications (14)

Synthesis of Some Quinoxaline Sulfonamides as a Potential Antibacterial Agent

Festus O. Taiwo, Craig A. Obafemi & David A. Akinpelu · Journal of Pharmaceutical Research International · 2021

Aims: This studies aims at the synthesis of new heterocyclic systems and study its biological and pharmacological properties. Objective: This study was designed to synthesized some quinoxaline-2,3-dione with sulfonamide moiety, characterize the synthesized compounds, and study th...

Open access Research Article 10.9734/jpri/2021/v33i51B33521

Synthesis and Antibacterial Potency of Some 3-methyl-2-oxo-1,2-dihydroquinoxaline-6- sulfonohydrazone Derivatives

Festus O. Taiwo, Olawatayo E. Abioye, Craig A. Obafemi & David A. Akinpelu · Journal of Advances in Microbiology · 2023

Studies on the synthesis of some sulfa quinoxaline has generate a considerable reputation as a result of their outstanding biochemical properties. This recent study was designed to prepared some sulfa quinoxaline hydrazone derivatives and studying their antimicrobial potency. The...

Open access Research Article 10.9734/jamb/2023/v23i11779

Recent Advances on the Synthesis, Reactions and Evaluation of the Pharmacological Properties of Quinoxaline, Quinoxaline-2-One and Quinoxaline-2,3-Dione

Festus O. Taiwo, David A. Akinpelu & Craig A. Obafemi · International Research Journal of Pure and Applied Chemistry · 2021

The review article attempts to give recent advances on quinoxaline and its derivatives. Some pathways to the synthesis of quinoxaline, quinoxaline-2-one and quinoxaline-2,3-dione were reported using simple reactive quinoxaline synthon. In addition, the reactions, biological and t...

Open access Research Article 10.9734/irjpac/2021/v22i830427

Design, Synthesis and Antibacterial Potency of 3-(2-(Benzylidenehydrazinyl)-1-Phenylquinoxalin-2(1H)-one Derivatives

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · International Research Journal of Pure and Applied Chemistry · 2026

Context: Studies on the synthesis of quinoxalines remain of considerable interest because of their chemical and biological properties. Objective: This study was designed to synthesize  3-(2-(benzylidene)Hydrazinyl)-1-Phenylquinoxalin-2(1H)-One derivatives and to study their antib...

Open access Research Article 10.9734/irjpac/2026/v27i51028

Design, Synthesis and Biological Evaluation and Molecular Docking Study of (Z)-7-Nitro-1-Phenyl-3-((2-((1-Phenylethylidene) Amino) Ethyl) Amino) Quinoxalin-2(1H)-One Derivatives

F. O. Taiwo, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & Craig A. Obafemi · Journal of Pharmaceutical Research International · 2026

Aims: To synthesize  (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-one derivatives and evaluate their possible biological properties. Methods: The substituted (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-o...

Open access Research Article 10.9734/jpri/2026/v38i97867

Design, Synthesis and Antibacterial Evaluation of (E)-N-(3-methyl-6-nitroquinoxalin-2-yl)-4-((1-phenylethylidene) Amino) Benzenesulfonamide Derivatives

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · Journal of Pharmaceutical Research International · 2026

Antibiotic resistance has increased the need to investigate new antibacterial scaffolds. This study synthesized  a series of quinoxaline sulfonamide Schiff base derivatives, designated 1a–h, and evaluated their antibacterial activity against selected bacterial strains. The compou...

Open access Research Article 10.9734/jpri/2026/v38i87865

Synthesis of N,N-Dibenzyl-2-(2-Benzylidenehydrazinyl)-3-oxo-3,4-Dihydroquinoxaline-6-Sulfonamide Derivatives and Evaluation of Their Antimicrobial Activity

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · Journal of Advances in Microbiology · 2026

Quinoxaline derivatives are of considerable interest because of their diverse chemical and biological properties. This study Synthesized N,N-dibenzyl-2-(2-benzylidenehydrazinyl)-3-oxo-3,4-dihydroquinoxaline-6-sulfonamide derivatives and evaluated their antibacterial activity agai...

Open access Research Article 10.9734/jamb/2026/v26i91178

Synthesis of (E)-N2-(3-Methylquinoxalin -2-yl)-N5-(1-Phenylethylidene) Pyridine-2,5-Diamine Derivatives and Evaluation of Their Antimicrobial Activity

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · Journal of Advances in Microbiology · 2026

Background: Research on the synthesis of various quinoxaline derivatives has gained significant attention due to their remarkable chemical and biological properties. These compounds exhibit diverse reactivity, making them valuable in chemical synthesis, and they also show promisi...

Open access Research Article 10.9734/jamb/2026/v26i91175

Design, Synthesis and Antibacterial Evaluation of 3-oxo-2-[2-(1-phenylethylidene)hydrazinyl]-3,4-dihydroquinoxaline-6-sulfonyl Azide Derivatives

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · International Research Journal of Pure and Applied Chemistry · 2026

This study was designed to synthesized some 3-oxo-2-(2-(1-phenylethylidene)hydrazinyl)-3,4-dihydroquinoxaline-6-sulfonyl azide derivatives and study their antibacterial potentials on some bacterial strains. 3-oxo-2-(2-(1-phenylethylidene)hydrazinyl)-3,4-dihydroquinoxaline-6-sulfo...

Open access Research Article 10.9734/irjpac/2026/v27i51027

Design, Synthesis and Antibacterial Evaluation of (Z)-3-Methyl-2-Oxo-N-(2-((1-phenylethylidene) amino)ethyl)-1,2-Dihydroquinoxaline-6-Sulfonamide Derivatives

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · Annual Research & Review in Biology · 2026

Background: Multidrug-resistant bacteria continue to create a need for new antibacterial scaffolds, and quinoxaline-sulfonamide derivatives are of interest because of their reported biological activity. Aim: This study synthesized and characterized a series of (Z)-3-methyl-2-oxo-...

Open access Research Article 10.9734/arrb/2026/v41i92444

Design, Synthesis and Antibacterial Evaluation of (E)-4-methyl-N'-(1-phenylethylidene)tetrazolo[1,5-a] quinoxaline-8-sulfonohydrazide Derivatives

Festus O. Taiwo, Oluwatayo E. Abioye, Olajide B. Omoyeni, David A. Akinpelu & Craig A. Obafemi · Current Journal of Applied Science and Technology · 2026

Quinoxaline derivatives are of continuing interest because of their diverse biological properties and their suitability for structural modification. This study synthesized a series of (E)-4-methyl-N'-(1-phenylethylidene)tetrazolo[1,5-a]quinoxaline-8-sulfonohydrazide derivatives a...

Open access Research Article 10.9734/cjast/2026/v45i94753

Chemical Composition and In-vitro Antibacterial Activity of the Essential Oil of Nigerian Moringa oleifera Lam. Flowers

Olaoye S. Balogun, Rachael Y. Fadare, Olatomide A. Fadare, David A. Akinpelu & Craig A. Obafemi · European Journal of Medicinal Plants · 2017

Aims: To investigate the chemical composition and antibacterial activity of essential oil isolated from flowers of Moringa oleifera (MO) grown in Western Nigeria. Methodology: Gas chromatography–mass spectrometry (GC-MS) analysis was carried out for identification and determinati...

Open access Research Article 10.9734/EJMP/2017/31834

Phytochemical Analyzes from the Leaves of Bryophyllum pinnatum

Esther O. Faboro, Liqing Wei, Shaobo Liang, Armando G. McDonald & Craig A. Obafemi · European Journal of Medicinal Plants · 2016

Aims: To identify extractable components in the traditional medicinal plant, Bryophyllum pinnatum (BP). Methodology: The leaves of BP were sequentially extracted with non-polar (CH2Cl2) and polar (CH3OH) solvents. The extracts were derivatized to their volatile fatty acid methyl...

Open access Research Article 10.9734/EJMP/2016/26156

In Vitro Evaluation of Antioxidant and Anti-inflammatory Properties of Methanol and Dichloromethane Extracts of the Leaf of Globimetula oreophila

Esther O. Faboro, Idowu J. Olawuni, Bolajoko A. Akinpelu, Oluokun O. Oyedapo, Ezekiel O. Iwalewa & Craig A. Obafemi · Chemical Science International Journal · 2018

Aims: The study was designed to investigate the antioxidant and membrane stabilizing potentials of the leaf of Globimetula oreophila, with a view to providing scientific support for the acclaimed ethnomedicinal or traditional uses of the plant. Methodology: The study involved col...

Open access Research Article 10.9734/CSJI/2018/42051