The Potential Role of Selenoproteins in Modulating Malaria Parasite Resistance to Artemisinin-based Combination Therapies (ACTs) in Africa
Uchechukwu Richard Njoku & Chukwuma Raphael Ekeanyanwu · Asian Journal of Research in Biochemistry · 2025
This review synthesises current knowledge on the structure, function, and expression of Plasmodium falciparum selenoproteins, focusing on thioredoxin reductase (PfTrxR), and their role in mitigating artemisinin-induced oxidative damage. Resistance to artemisinin-based combination...
Open access
Research Article
10.9734/ajrb/2025/v15i4408