Tegumental Changes in Adult Schistosoma mansoni Induced by a New Imidazolidinic Derivative
Anekécia Lauro da Silva, Sheilla Andrade de Oliveira, Jamerson Ferreira de Oliveira, Edna de Farias Santiago, Antônio Sérgio Alves de Almeida Júnior, Íris Trindade Tenório Jacobi, Christina Alves Peixoto, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, Ivan da Rocha Pitta & Maria do Carmo Alves de Lima · Journal of Pharmaceutical Research International · 2014
Aims: Verify the potential of the schistosomicidal imidazolidine derivative (5Z)-3-(4-bromo-benzyl)-5-(4-chloro-benzylidene)-4-thioxo-imidazolidin-2-one. Study Design: In this study, we tested the imidazolidinic derivative 3 through in vitro evaluations, cytotoxicity assay and an...