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Chitralekha Saikumar

Publications (7)

Epidemiology & Prognostication of Acute Myeloid Leukemia (AML) in India – A Brief Review

E. Suguna, Chitralekha Saikumar & Florida Tilton · Journal of Pharmaceutical Research International · 2021

AML is represented by aggregation of ≥20% myeloid immature cells in the spongy marrow and most generally raise in the peripheral blood. A cytogenetic finding plays a vital role in the risk management and stratification of AML patients. AML is genetically and functionally a hetero...

Open access Research Article 10.9734/jpri/2021/v33i59B34423

Co-infection of Dengue and Chikungunya viruses: A Serological study from Ananthapuramu District, Andhra Pradesh

Adireddi Paradesi Naidu, Chitralekha Saikumar, Kalavathy Victor, G Sumathi & N. S. Muthiah · Journal of Pharmaceutical Research International · 2021

Introduction: It is observed that the infections of Dengue and Chikungunya were rising in many parts of India. Aedes aegypti mosquitoes are common vectors for dengue virus (DENV) and CHIK virus (CHIKV). In areas where both viruses co circulate, they can be transmitted together. T...

Open access Research Article 10.9734/jpri/2021/v33i59B34363

Comparison of NS1 Antigen Detection by Rapid Immunochromatography Test and ELISA for Early Diagnosis of Dengue at a Government General Hospital, Ananthapuramu

Adireddi Paradesi Naidu, Chitralekha Saikumar, G. Sumathi, Kalavathy Victor & N. S. Muthiah · Journal of Pharmaceutical Research International · 2021

Background: The incidence of Dengue hemorrhagic fever, Dengue shock syndrome associated with Dengue can be reduced by diagnosing Dengue early and by initiating early treatment to Dengue patients. This study was conducted to compare results of NS1 antigen rapid test and ELISA in c...

Open access Research Article 10.9734/jpri/2021/v33i57B34069

Study on the Prevalance, Identification and Antibiogram of Enterococci Isolated from the Heterogenous Clinical Samples in a Tertiary Care Hospital

Binish Gulzar & Chitralekha Saikumar · Journal of Pharmaceutical Research International · 2021

The rise in Pantone-Valentine leucocidin (PVL) and gAMMA-haemolysin (Hlg) producing Enterococcus spp., among the people is a serious concern on evolution of antibiotic resistance. Recent reports suggested that the synergistic association of PVL toxin and necrotic lesions that lea...

Open access Research Article 10.9734/jpri/2021/v33i25B31458

Isolation and Identification of Uropathogenic E. coli and its Antimicrobial Susceptibility Pattern with Special Reference to Extended Spectrum Beta-Lactamases (Esbl)

V. Naveen Kumar & Chitralekha Saikumar · Journal of Pharmaceutical Research International · 2021

Urinary tract infections (UTI) are the most common bacterial infection among the humans. One of the most important factors impacting the management of UTI over the past decade is emergence of anti-microbial resistance among uropathogens. ESBL production is one of the most common...

Open access Research Article 10.9734/jpri/2021/v33i24A31431

Detection of Gram Negative Bacilli Producing Extended Spectrum Beta Lactamase on Intensive Care Unit at Tertiary Care Hospital

M. Nishanthy & Chitralekha Saikumar · Journal of Pharmaceutical Research International · 2021

Antimicrobial resistance is a budding threat worldwide. The every class of antibiotic agents must have resistance mechanisms.The principal mechanism for resistance to the β-lactam antibiotics in gram-negative bacteria is the production of β-lactamase. The creation of extended-spe...

Open access Research Article 10.9734/jpri/2021/v33i23B31413

Urinary Isolates and Antifungal Susceptibility Pattern of Candida species Isolated from Patients in Tertiary Care

A. Arasi Samyuktha, V. Illamani & Chitralekha Saikumar · Journal of Pharmaceutical Research International · 2021

Community-acquired urinary tract infections (UTIs) are fastidious growing infections caused by Candida fungal overgrowth that frequently occur in immunosuppressed hospital patients. Although many factors account for the increases in these fungal infections, the leading causes inc...

Open access Research Article 10.9734/jpri/2021/v33i25A31451