Chithara Anil

The NLRP3 Inflammasome in Periodontitis: A Critical Appraisal of Innate Immune Mechanisms Linking Microbial Challenge to Periodontal Inflammation and Alveolar Bone Loss

Prakash Pai Gurpur, Mundoor Manjunath Dayakar, Chithara Anil & Pallavi Holal · International Journal of Research and Reports in Dentistry · 2026

Periodontitis is a dysbiosis-driven chronic inflammatory disease in which host immune activity, rather than microbial presence alone, determines the destruction of the tooth-supporting apparatus and the resorption of alveolar bone. The nucleotide-binding oligomerisation domain, l...