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Chika L. Uche

Publications (6)

Implication of Nephropathy in Sickle Cell Anaemia

Chika L. Uche, Edmund O. Ezirim, Abali O. Isaiah & Augustine I. Airaodion · International Journal of Advances in Nephrology Research · 2022

Aim: This study sought to investigate the effect of sickle cell anemia on kidney using endogenous biomarkers. Methodology: This study is a case-control study which enrolled 60 sickle cell anemia patients (30 males and 30 females) in a stable state at the Obafemi Awolowo Universit...

Open access Research Article

Sickle Cell Anemia Contributes to Liver Abnormality

Chika L. Uche, Abali O. Isaiah, Edmund O. Ezirim & Augustine I. Airaodion · International Journal of Research and Reports in Hematology · 2022

Aim: This study sought to investigate the implication of sickle cell anemia on hepatic biomarkers. Methodology: This is a case-control study which enrolled 60 sickle cell anemia patients (30 males and 30 females) in a stable state at the Obafemi Awolowo University Teaching Hospit...

Open access Research Article

Xylopia aethiopica Fruit Increased Prothrombin Time, Activated Partial Thromboplastin Time and Erythrocyte Sedimentation Rate of Wistar Rats

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Prince C. Unekwe & Ifeoma N. Nweke · International Journal of Research and Reports in Hematology · 2022

Background: Traditionally, the use of Xylopia aethiopica fruit for therapeutic purposes is on the increase without any consideration of its safety and toxicity. Aim: This study was therefore designed to examine its effect on coagulation factors of Wistar rats. Methodology: The fr...

Open access Research Article

Alterations in Female Reproductive Hormones of Wistar Rats Sequel to the Administration of Xylopia aethiopica Fruit

Emmanuel O. Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Uloaku Ogbuagu, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Research Journal of Gynaecology and Obstetrics · 2022

Aim: This present study was designed to examine the impact of Xylopia aethiopica fruit on the reproductive hormones of female Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanol as solvent. The lethal dose of...

Open access Research Article

Knowledge, Attitude and Practice of Breast Self-Examination (BSE) among Women in an Urban City in Abia State, Nigeria

Ejiro C. Iwuoha, Ngozi C. Ekeleme & Chika L. Uche · Asian Journal of Medicine and Health · 2021

Background: Early diagnosis of breast cancer has been associated with better outcomes in diagnosed cases. Breast self-examination (BSE) is an inexpensive but effective method of identifying breast masses that may be cancerous. Objectives: To identify the knowledge, attitude and p...

Open access Research Article 10.9734/ajmah/2020/v18i1230281

Effect of Ethanol Extract of Xylopia aethiopica Fruit on Oxidative Stress Indices of Wistar Rats

Emmanuel O. Ogbuagu, Uloaku Ogbuagu, Augustine I. Airaodion, Chika L. Uche, Edmund O. Ezirim, Ifeoma N. Nweke & Prince C. Unekwe · Asian Journal of Immunology · 2022

Background: The use of Xylopia aethiopica fruit in folklore medicine is on the increase without caution of its toxicity. Aim: This present study tends to assess its effect on the oxidative stress biomarkers of Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dr...

Open access Research Article