Role of CaMK II α in the Injury of Dorsal Root Ganglion Neurons Induced by Ropivacaine Hydrochloride in the Dorsal Root Ganglion of Rats
Wu Zhaoxia, Chen Meixin, Li Yiqun, Yang Shuxuan & Wen Xianjie · Journal of Pharmaceutical Research International · 2021
Objective: To investigate whether CaMKⅡα participates in the dorsal root ganglion neurotoxicity induced by ropivacaine hydrochloride. Methods: DRG neurons were isolated from 1-day-old SD rats and cultured in vitro. pAd-shRNA-CaMKⅡα-DRG cells were constructed by RNA interference t...
Open access
Research Article
10.9734/jpri/2020/v32i4731106