Charles C. Diovu

Translational Insight into Gongronema latifolium-silver Nanoparticles: Linking in vivo Safety to Molecular Antimalarial Mechanism

Goodnews Onyedikachi Ikeh, Jasmine Kayanian, Nkoyo Imelda Nubila, Charles C. Diovu, Sunday Kaura, Ndidiamaka H. Okorie & Ibeabuchi J. Ali · Journal of Advances in Medical and Pharmaceutical Sciences · 2026

Building upon our recent finding that the biopolymer matrix of green-synthesized silver nanoparticles (AgNPs) dictates their exceptional safety (LD50 > 5000 mg/kg) and antimalarial efficacy, this study employed a computational framework to de-convolute the molecular identity o...

Open access Research Article 10.9734/jamps/2026/v28i3850

Molecular Spectroscopic (FTIR and UV-Vis) and Hyphenated Chromatographic (GC–MS) Characterization of Bioactive Compounds Present in Different Solvent Fractions of Extract of Leaf of Cola hispida Brenan & Keay Sterculiaceae

Goodnews Onyedikachi Ikeh, Njideka Ifeoma Ani, Vincent Uchechukwu Ude, Jude Kosisochukwu Onyia, Charles C. Diovu & Rita Chiamaka Okpoto · South Asian Research Journal of Natural Products · 2025

Cola hispida Brenan & Keay (Sterculiaceae), a tropical plant native to West and Central Africa, is widely used in traditional medicine for its therapeutic properties, yet its phytochemical composition remains underexplored. This study investigates the bioactive compounds in d...

Open access Research Article 10.9734/sarjnp/2025/v8i2194

Biogenic Synthesis and Comparative Assessment of the Antimicrobial Activities of Silver and Zinc Nanoparticles of Dialium guineense Leaf Extract against Human Pathogens

Goodnews Onyedikachi Ikeh, Ugwu PE, Rita Chiamaka Okpoto, Njoku EA, Charles C. Diovu & Adonu CC · Journal of Complementary and Alternative Medical Research · 2024

Aim: The study aimed to perform a comparative evaluation of the antimicrobial activities of green synthesis of silver and zinc nanoparticles. Study Design: Experimental. Methodology: A biogenic and facile method of synthesis of silver and zinc oxide nanoparticles (DGL—SNPs and DG...

Open access Research Article 10.9734/jocamr/2024/v25i12607

Thermodynamic and Kinetic Elucidation of the Biogenic Capping Mechanism: Evidence of Ordered Self-assembly in Gongronema latifolium-Silver Nanoparticles

Goodnews Onyedikachi Ikeh, Hannah Ndidiamaka Okorie, Ibeabuchi J. Ali, Jasmine Kayanian, Rita C. Okpoto, Charles C. Diovu & Sunday Kaura · Physical Science International Journal · 2026

While our previous research successfully established the exceptional in vivo safety profile (LD50 > 5000 mg/kg) and the potent antimalarial efficacy of silver nanoparticles synthesized using Gongronema latifolium, and subsequently identified both Sarsasapogenin and Cinchonidin...

Open access Research Article 10.9734/psij/2026/v30i2938