Carmen de Groote

Differential Effects of Anaesthesia on the phMRI Response to Acute Ketamine Challenge

Duncan J. Hodkinson, Carmen de Groote, Shane McKie, J. F. William Deakin & Steve R. Williams · Journal of Advances in Medicine and Medical Research · 2012

Aims: Pharmacological-challenge magnetic resonance imaging (phMRI) is powerful new tool enabling researchers to map the central effects of neuroactive drugs in vivo. To employ this technique pre-clinically, head movements and the stress of restraint are usually reduced by maintai...