High-Dose Intravenous Epoprostenol and Adjunct Therapies for Refractory Raynaud’s Phenomenon Associated with Anti-Jo-1 Antibodies: A Case Report
Andy Pan, Imran Khan, Marlene Mansour, Bernadett Kovacs, Caitlin Richler, Christine Landry, Kimberley Do, Sydney Morin, Deb Purkayastha, Melissa Varsava, Emma Baun & Pierre Thabet · International Journal of Medical and Pharmaceutical Case Reports · 2025
This case report highlights the use of intravenous high-dose Epoprostenol for managing severe digital ischemia in a patient diagnosed with antisynthetase syndrome (ASyS) exhibiting anti-Jo1 antibodies positivity, emphasizing its vasodilatory benefits and challenges with tolerabil...