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C. O. Esimone

Publications (7)

Antimicrobial Activity of Crude Methanol Extract of Fecal Droppings of Common House Lizard/Gecko (Hemidactylus frenatus)

K. G. Ngwoke, P. M. Eze & C. O. Esimone · Journal of Applied Life Sciences International · 2015

Aims: This study was carried out to evaluate the antimicrobial activity of methanol extract of fecal droppings of common house lizard/gecko (Hemidactylus frenatus). Methodology: The antimicrobial activity of the methanol extract of fecal droppings of common house lizard/gecko was...

Open access Research Article 10.9734/JALSI/2015/13059

Evaluation of the Paper Quality of Antibacterial Discs Commercially Available in Nigeria

P. M. Eze, E. E. Ajaegbu & C. O. Esimone · Journal of Scientific Research and Reports · 2014

Aim: A wide range of antibacterial discs are commercially available in Nigeria that are either manufactured locally or imported. The quality of papers used in the manufacture of these discs can play a considerable role in their performance during antibiotic susceptibility testing...

Open access Research Article 10.9734/JSRR/2014/9078

Optimized Artemether-loaded Anhydrous Emulsion

N. C. Obitte, L. C. Rohan, C. M. Adeyeye & C. O. Esimone · Journal of Pharmaceutical Research International · 2013

Objective: The objectives of this study were to identify stable anhydrous emulsions via pseudo ternary phase diagram, optimize artemether-loaded batches using factorial design and subsequently evaluate the antimalarial activity. Methodology: Using labrasol®, triacetin® and laurog...

Open access Research Article 10.9734/BJPR/2014/5279

Antimicrobial Resistance Evaluation of Organisms Isolated from Liquid Herbal Products Manufactured and Marketed in South Eastern Nigeria

N. T. Ujam, A. N. Oli, M. N. Ikegbunam, M. U. Adikwu & C. O. Esimone · Journal of Pharmaceutical Research International · 2013

Objective: To determine the susceptibility and resistance pattern of bacteria and fungi isolates obtained from herbal anti-infective liquid preparations manufactured and marketed in South-East Nigeria to conventional antibiotics. Study Design: Experimental Place and Duration of t...

Open access Research Article 10.9734/BJPR/2013/3554

Evaluation of the Quality of Commercial Antibacterial Discs Available in Nigeria

P. M. Eze, E. E. Ajaegbu, P. C. Ejikeugwu, R. N. Egbuna, C. C. Abba & C. O. Esimone · Journal of Pharmaceutical Research International · 2014

Aims: This study was undertaken to compare the quality and efficacy of six brands of antibacterial discs that are commercially available in Nigeria. Methodology: The brands evaluated include two foreign brands (Oxoid and Abtek) and four local brands (Optudisc, Polydisc, Maxidisc...

Open access Research Article 10.9734/BJPR/2014/10900

Quality Assessment of Some Brands of Tetanus Toxoids Marketed in Open Markets in South-Eastern Nigeria

V. U. Chigozie, P. M. Eze, C. R. Chukwunwejim, C. C. Abba, C. S. Nworu & C. O. Esimone · Journal of Pharmaceutical Research International · 2014

Aims: This study was designed to verify the immunogenicity (potency) and the safety of tetanus toxoid vaccines marketed in three large open drug markets in South-Eastern Nigeria. Methodology: Tests for Sterility, formaldehyde concentrations, specific toxicity, endotoxin, and immu...

Open access Research Article 10.9734/BJPR/2014/10901

Antibacterial Evaluation of Aqueous and Ethanol Extracts of Ocimum gratissimum and Carica papaya

E. Evwierhurhoma, M. C. Ugwu, C. O. Eze, C. Annie, F. O. Enwa, P. M. Eze & C. O. Esimone · Annual Research & Review in Biology · 2015

Aims: This study was carried out to evaluate the antibacterial activity of aqueous and ethanol leaf extracts of Ocimum gratissimum and Carica papaya against selected clinical isolates of Gram-negative bacteria and to also determine the phytochemical constituents of the plants. Me...

Open access Research Article 10.9734/ARRB/2015/16481