C. G. Nwaigwe

Controlled Release Binary and Ternary HPMC-HPC-Gelucire® 50/13 Hybrids Based Solid Dispersions of Indomethacin: In vitro Evaluation and In vivo Anti-inflammatory Studies

J. N. Reginald-Opara, K. C. Ofokansi, F. C. Kenechukwu, C. G. Nwaigwe & A. M. Nnogo · Journal of Pharmaceutical Research International · 2018

Aim: The aim of this study is to formulate and evaluate solid dispersions of indomethacin based on Gelucire 50/13, Hydroxylpropyl methylcellulose and/or Hydroxylpropyl cellulose hybrid binary or ternary system, with a view of enhancing oral bioavailability, sustaining drug releas...