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C. C. N. Vincent

Publications (17)

Prevalence and Pattern of Psychoactive Substance use among Senior Secondary School Students in Community Secondary School, Umuna, Orlu L.G.A

C. C. N. Vincent, Emmanuel I. Obeagu, Ifeyinwa Stephina Agu & Agnes Chinyere Onyekachi-Chigbu · Journal of Pharmaceutical Research International · 2021

Psychoactive substance use among Secondary School Students has become an increasing public health problem in many countries. This study assessed the prevalence and patterns of psychoactive substance use among senior secondary school students of community secondary school, Umuna....

Open access Research Article 10.9734/jpri/2021/v33i57A33969

Adherence to Antiretroviral Therapy among HIV/AIDS in Federal Medical Centre, Owerri

C. C. N. Vincent, Emmanuel I. Obeagu, Ifeyinwa Stephina Agu, Ngozi Chidinma Ukeagu & Agnes Chinyere Onyekachi-Chigbu · Journal of Pharmaceutical Research International · 2021

The research is set out to determine the adherence to antiretroviral therapy among HIVAIDS in Federal Medical Clinic Owerri. The purpose of the study was to assess patients knowledge of benefits of Highly Active antiretroviral Regimen, determine level of adherence among the HIV p...

Open access Research Article 10.9734/jpri/2021/v33i57A34007

Therapeutic Targets In Breast Cancer Signaling: A Review

Emmanuel I. Obeagu, Quratulain Babar, C. C. N. Vincent, Chikwendu Lawrence Udenze, Richard I. Eze, Chukwum J. Okafor, Bart I. Ifionu, Augustine Amaeze Amaeze & Florence Ngozi Amaeze · Journal of Pharmaceutical Research International · 2021

For women, the most dominant type of cancer is breast cancer and perhaps one of the most recognizedreasons of death. This is a disorder of many distinct traits, many of which are known as positive hormone receptor, human epidermal receptor-2 (HER2+), and three negative breast can...

Open access Research Article 10.9734/jpri/2021/v33i56A33889

Pulmonary Embolism in Covid-19 Pandemic: A Threat to Recovery of the Infected Patients

Emmanuel I. Obeagu, Quratulain Babar, C. C. N. Vincent, Chukwum J. Okafor, Richard Eze, Udunma Olive Chijioke, Adaobi Maryann Ibekwe & Immaculata Ogochukwu Uduchi · Journal of Pharmaceutical Research International · 2021

Severe Acute Respiratory Syndrome Coronavirus 2 is a new type of coronavirus that can cause Coronavirus Disease 2019 (Covid-19) and is associated with an increased risk of thrombosis-related pulmonary embolism. Globally, doctors have revised their management strategies for suspec...

Open access Research Article 10.9734/jpri/2021/v33i42A32388

Studies of Serum Calcium, Inorganic Phosphate and Magnesium Levels in Lactating Mothers in Owerri

Ukamaka Edward, Emmanuel I. Obeagu, Hope M. Okorie, C. C. N. Vincent & Yakubu Sunday Bot · Journal of Pharmaceutical Research International · 2021

This study was aimed at evaluating the serum levels of Calcium, Inorganic phosphate and Magnesium together with the Body Mass Index (BMI) in lactating mothers in Owerri. A total of sixty subjects were recruited. Thirty were lactating subjects while thirty were apparently healthy...

Open access Research Article 10.9734/jpri/2021/v33i41B32360

Knowledge and Practice of Childhood Immunization among Men with Infants in Enugu Metropolis

Chekwube Catherine Agu, C. N. Onwasigwe, Emmanuel I. Obeagu, C. C. N. Vincent, Udunma Olive Chijioke, Calista Ndidi Adike, Chukwum J. Okafor, Adaobi Maryann Ibekwe, Lizzy Agunwah & Confidence Ogechi Anyanwu · Journal of Pharmaceutical Research International · 2021

Background: Immunization is the process by which a person’s immune system is fortified and made resistant to an infectious disease/ agent. Immunization saves millions of lives. It is the most important means of preventing childhood morbidity and mortality. This study investigated...

Open access Research Article 10.9734/jpri/2021/v33i39B32174

Evaluation of Catalase and Manganese in Type 2 Diabetic Patients in University of Port Harcourt Teaching Hospital

Arvin Nwakulite, Emmanuel I. Obeagu, Richard Eze, C. C. N. Vincent, Ejike Felix Chukwurah, Chukwuma J. Okafor, Adaobi Maryann Ibekwe, Calista Ndidi Adike, Ufuoma Chukwuani & Bart I. Ifionu · Journal of Pharmaceutical Research International · 2021

This study was carried out to evaluate catalase and manganese in type 2 diabetes mellitus patients. A total of 40 subjects Were included in this study. This comprised of equal number of male and female subjects respectively. Enzyme linked immunosorbent assay (ELISA) method was us...

Open access Research Article 10.9734/jpri/2021/v33i30B31638

Evaluation of Iron Status, Haemoglobin and Protein Levels of Pregnant Women in Owerri Metropolis

I. L. Okoroiwu, Jane Ugochi Chinedu-Madu, Emmanuel Ifeanyi Obeagu, C. C. N. Vincent, O. M. T. B. Ochiabuto, Adaobi Maryann Ibekwe, Chukwudi Ofodile Amaechi, Chekwube C. Agu, Nonyelum Vivian Anoh & Nkiruka Millicent Amadi · Journal of Pharmaceutical Research International · 2021

The study was done to determine iron status, haemoglobin and protein levels of pregnant women in owerri metropolis. A total of 100 pregnant women were recruited for this study. The mean Hb levels in group 1, group 2, and group 3· were 12.00±1.68g/dl, 10.06±1.J4g/dl and 10.96±1.19...

Open access Research Article 10.9734/jpri/2021/v33i27A31491

Metastasis Relapse in Synovial Sarcoma of Parotid Gland Followed by Neuropathies and Tissue Damage: A Case Report

Quratulain Babar, Emmanuel I. Obeagu, Chikwendu Lawrence Udenze, Bart I. Ifionu, C. C. N. Vincent, Chukwum J. Okafor, Emmanuel Ikechukwu Nwobodo & C. O. C. Ibe · Journal of Pharmaceutical Research International · 2021

Synovial sarcomas are a heterogeneous group of tumors, accounting for 1-2% of adult cancers worldwide. Formation of synovial sarcoma after tissue and nerve injury, radiations induced neuropathies and latent metastasis is those events which are still controversial and need more re...

Open access Research Article 10.9734/jpri/2021/v33i54A33726

The Dynamics of Innate and Adaptive Immune Response to Sars Cov-2 Infection and Its Limitations in Human Beings

Akpanda Etido, Emmanuel I. Obeagu, Chukwum J. Okafor, Udunma Olive Chijioke, C. C. N. Vincent & Genevieve C. Mojo-Eyes · Journal of Pharmaceutical Research International · 2021

This article deals with the dynamics of the innate and adaptive immune response to severe acute respiratory syndrome coronavirus 2 (SARSCoV2) infection. SARSCoV2 is the viral factor that causes the current global coronavirus pandemic disease 2019 (COVID2019). In terms of person-t...

Open access Research Article 10.9734/jpri/2021/v33i45A32708

Evaluation of Factor Viii and Factor IX Activity among Primary School Children in Owerri, Imo State, Nigeria

I. L. Okoroiwu, Emmanuel I. Obeagu, Lilian Nneka Egbuobi, Adaobi Maryann Ibekwe, C. C. N. Vincent, Bright Chukwuebuka Unaeze, Calista Ndidi Adike, Udunma Olive Chijioke, Chukwuma J. Okafor, Ayomide Olusiji Soremi, Ejike Felix Chukwurah, Bart I. Ifionu & Confidence Ogechi Anyanwu · Journal of Pharmaceutical Research International · 2021

The values of factor VIII (FVIII) and factor IX (FIX) were evaluated among some primary school children in Owerri zone Imo State. The aim was to assess deficiency state or reduction in activity among these children. A total of two hundred and ten (210) venous blood samples were c...

Open access Research Article 10.9734/jpri/2021/v33i34B31864

Evaluation of Copper Status and Some Red Cell Parameters of Pregnant Women in Enugu State, South Eastern Nigeria

Richard Eze, Emmanuel I. Obeagu, Arvin Nwakulite, I. L. Okoroiwu, C. C. N. Vincent, Chukwuma J. Okafor, Ejike Felix Chukwurah, Udunma Olive Chijioke & Chukwudi Ofodile Amaechi · Journal of Pharmaceutical Research International · 2021

Copper is an essential trace mineral (micronutrient) that is naturally present in some foods and is available as a dietary supplement. Pregnancy, also known as gestation, is the time during which one or more offspring develops inside a woman.This study was desiged to assay the co...

Open access Research Article 10.9734/jpri/2021/v33i30A31616

Age-Related Haematological Variations in Patients with Asymptomatic Malaria in Akure, Ondo State, Nigeria

Emmanuel Ifeanyi Obeagu, Ayomiposi Ibironke Busari, Immaculata Ogochukwu Uduchi, I. A. Ogomaka, Adaobi Maryann Ibekwe, C. C. N. Vincent, Udunma Olive Chijioke, Chukwuma J. Okafor, Henshaw U. Okoroiwu & Calista Ndidi Adike · Journal of Pharmaceutical Research International · 2021

Background: Malaria is a life-threatening infectious disease of widespread burden. Malaria remains a leading communicable disease in the developing countries of the world. It occurs mostly in the tropical and subtropical regions and accounts for considerable morbidity and death....

Open access Research Article 10.9734/jpri/2021/v33i42B32441

Studies on Pancreatic Gene Expression in Diabetic Rats Treated with Moringa oleifera Leaf

Arvin Nwakulite, Emmanuel Ifeanyi Obeagu, H. U. Nwanjo, D. C. Nwosu, I. N. Nnatuanya, C. C. N. Vincent, Chukwudi Ofodile Amaechi, Ogochukwu, Mary-Theodora Barbara Ochiabu, Adaobi Maryann Ibekwe, Chukwuma J. Okafor, Getrude Uzoma Obeagu & Nkiruka Millicent Amadi · Journal of Pharmaceutical Research International · 2021

Moringa oleifera leaf have been used for treatment of diabetes, in this work we studied pancreatic gene expression. The gene expression was done by PCR machine. The plant was harvested from garden within Madonna University and was identified in the Department of Pharmacognosy of...

Open access Research Article 10.9734/jpri/2021/v33i28A31512

Gender-Based Assessment of Haematological Parameters of Obese Individuals in Omisanjana Area of Ado Ekiti, Ekiti State, Nigeria

Emmanuel I. Obeagu, Precious Omotunde, Getrude Uzoma Obeagu, Richard I. Eze, Ukamaka Edward, Chukwum J. Okafor, C. C. N. Vincent, Ejike Felix Chukwurah & Blessing Oluchi Akalonu · Journal of Pharmaceutical Research International · 2021

Background: Obesity is a serious health problem, it increases heart-related diseases and its prevalence continues to increase due to genetic and lifestyle influences. This study aims to evaluate the hematological parameters of obese individuals based on gender in the Omisanjana r...

Open access Research Article 10.9734/jpri/2021/v33i43A32500

An Update on Transfusion Related Immunomodulation (TRIM) in a Time of COVID- 19 Pandemic

Emmanuel I. Obeagu, Quratulain Babar, Immaculata Ogochukwu Uduchi, Adaobi Maryann Ibekwe, Udunma Olive Chijioke, Chukwum J. Okafor & C. C. N. Vincent · Journal of Pharmaceutical Research International · 2021

Recipients' immune systems are triggered by blood and blood component therapy. Transfusion-related immunomodulation (TRIM) is a complicated immunological response to transfusion that results in immunosuppression. The mechanisms of TRIM include the presence of residual white blood...

Open access Research Article 10.9734/jpri/2021/v33i42A32394

Studies on Molecular Docking of Moringa Oleifera Leaf Phytochemical Constituents on Alpha Glucosidase, Alpha Amylase and Dipeptidyl Peptidase

Arvin Nwakulite, Emmanuel Ifeanyi Obeagu, H. U. Nwanjo, D. C. Nwosu, I. N. Nnatuanya, Richard Eze, Getrude Uzoma Obeagu, C. C. N. Vincent, Chukwudi Ofodile Amaechi, Chukwuma J. Okafor, Vivian Ezeoru, Ufuoma Chukwuani & Mathew E. Adu · Journal of Pharmaceutical Research International · 2021

Moringa oleifera leaf have been used for treatment of diabetes, in this work we studied pancreatic gene expression, trace elements, enzymatic antioxidants, kidney injury biomarkers in streptozocin induced diabetic rats treated with M. oleifera  leaf powder and molecular ducking o...

Open access Research Article 10.9734/jpri/2021/v33i28A31527