Aim: Interest in phospholipase A2 has continued to rise since its biotechnological potentials and involvement in the pathogenicity of Trypanosoma species were recognized, therefore this study was designed to investigate the vaccine potential of Trypanosoma brucei PLA2 gene contai...
Open access
Research Article10.9734/AJMAH/2016/30065
Aim: The study explored the diversity of Plasmodium falciparum Merozoite Surface Protein 1 (msp-1) gene sequence and delineated the K1 allele occurrence and profile. The Plasmodium falciparum msp-1 gene encodes an antigen that is being proposed as a major vaccine candidate agains...
Open access
Research Article10.9734/ijpr/2023/v12i6260
Ishaya Yohanna Longdet, Richard Joseph Kutshik, Ngozi Yvonne Chibundu, Bitrus Yakubu & Dinci Tyem Davou·South Asian Journal of Parasitology·2020
Aim: To explore the molecular characteristics of glutamine rich protein (GLURP) gene in Plasmodium berghei NK65 and compare its genetic relatedness with those of Plasmodium falciparum. The GLURP is a key surface antigen and its gene a genetic marker for genotyping in malaria epid...
Nelson J. Nwankwo, Joel Paul, Shangshikmwa K. Gaknung, Timloh Fakdul, Mercy O. Simon, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Asian Journal of Biotechnology and Genetic Engineering·2024
Aim: This study investigates mutations at codon 540 in the dihydropteroate synthetase (540dhps) gene that may confer resistance to sulfadoxine-pyrimethamine treatment by Plasmodium falciparum in Jos. Study Design: The research employs a cross-sectional study design. Place and Dur...
Joel Paul, Nelson J. Nwankwo, Mercy O. Simon, Shangshikmwa K. Gaknung, Timloh Fakdul, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Journal of Advances in Biology & Biotechnology·2023
Aim: The aim of this study was to explore the Plasmodium falciparum Artemisinin Resistant Gene (Pfkelch13) in malaria cases in Jos and profile the nature of the mutations. The Plasmodium falciparum kelch13 gene is a potential molecular marker for tracking artemisinin-resistant ma...
Open access
Research Article10.9734/jabb/2023/v26i10661
Timloh Fakdul, Shangshikmwa K. Gaknung, Mercy O. Simon, Nelson J. Nwankwo, Joel Paul, Hafsat S. Jagab, Daniel G. ThankGod, Dinci T. Davou, Mary M. Mankilik, Richard J. Kutshik, Bitrus Yakubu & Ishaya Y. Longdet·Asian Journal of Research in Biochemistry·2024
Background: Malaria remains a significant health threat globally, with Plasmodium falciparum being the predominant and lethal parasite in Africa. Nigeria is still faced with ongoing cases of asymptomatic malaria, hindering effective control measures. Aim: The aim was to generate...
Open access
Research Article10.9734/ajrb/2024/v14i1273