Irinotecan Engineered Proniosomes: In vitro and In vivo Characterization
Prakash Goudanavar, B. Ramesh, Santosh Fattepur & Nagaraja Sreeharsha · Journal of Pharmaceutical Research International · 2021
Objective: The focus of this research has been to improve efficacy, decrease tolerance and increase the irinotecan pharmacokinetic profile. Methods: Proniosomesformulated with various surfactants, cholesterol and dicetyl phosphate using the slurry method. A slurry process was use...