B. R. Mahalakshmi

PolyG (Polyglycine) Repeat and Human Diseases: An Update on the Biology, Diseases Mechanisms and Current Therapeutic Interventions

B. R. Mahalakshmi, J. N. Sharada Devi, D. J. Shruthi, B. K. Manjunath & H. B. Kiran Kumar · Journal of Applied Life Sciences International · 2026

Nucleotide repeats known as short tandem repeats (STRs) can be found in both coding and non-coding areas of the human genome such a polyglutamine (polyQ), polyglycine (polyG) and polyalanine (PolyA). PolyG repeat expansions, are caused by GGC repeat expansions leading to numerous...

Open access Research Article 10.9734/jalsi/2026/v29i2773

Chromosomal Rearrangements and Genetic Fusion–Fission Dynamics in Eukaryotes: Mechanisms, Evolution, and Functional Implications

M D Priya, B. R. Mahalakshmi, J. N. Sharada Devi, Sumarani, H B Divyashree & H. B. Kiran Kumar · Annual Research & Review in Biology · 2026

Structural changes in chromosomes arise through various processes and are often associated with specific genomic features that promote genetic instability. Chromosomal rearrangements have long been recognised as having significant effects on fertility and increasing the risk of h...

Open access Research Article 10.9734/arrb/2026/v41i42386