Adolescence is a developmentally sensitive interval in which linear growth, pubertal endocrine maturation, body-composition change, and rapid skeletal mineral accrual occur while experimentation with nicotine, tobacco, and cannabis commonly begins. This critical narrative review...
Open access
Research Article10.9734/jsrr/2026/v32i94504
The developing heart is unusually exposed to the nutritional environment because it must sustain a continuously rising cardiac output while its own mass, metabolic machinery and extracellular matrix are still being assembled. Both ends of the nutritional spectrum leave a cardiac...
Open access
Research Article10.9734/jammr/2026/v38i96198
The intestinal microbial community assembles during the same developmental window in which adiposity, islet autoimmunity, hepatic lipid handling and linear growth are established, and this temporal coincidence has encouraged the view that microbial variation is a modifiable deter...
Open access
Research Article10.9734/jammr/2026/v38i96196
Serum ferritin is among the most frequently requested laboratory investigations in general medicine, yet its interpretation rests on assumptions that the accumulated evidence supports only in part. The analyte is used simultaneously as a surrogate for body iron stores, as an acut...
Open access
Research Article10.9734/ajrb/2026/v16i5513
Giardiasis in childhood ranges from self-limited gastroenteritis to persistent, recurrent, or clinically silent intestinal infection. Its contribution to growth faltering remains difficult to isolate because exposure is concentrated in settings where dietary insufficiency, repeat...
Open access
Research Article10.9734/ajpr/2026/v16i8562
Schistosomiasis affects more children than any other neglected tropical disease, yet its consequences for somatic growth and endocrine function during childhood and adolescence remain less thoroughly characterised than its recognised effects on anaemia and hepatosplenic disease....
Open access
Research Article10.9734/sajp/2026/v9i3305
Maternal hypertensive disorders of pregnancy (HDP)—encompassing chronic hypertension, gestational hypertension, preeclampsia, and superimposed preeclampsia—complicate a substantial proportion of pregnancies worldwide and are increasingly recognised as determinants of offspring he...
Open access
Research Article10.9734/ajpcb/2026/v9i1219
Delayed puberty in adolescent boys arises most commonly from a self-limited maturational variant, constitutional delay of growth and puberty, but must be distinguished from permanent hypogonadotropic or hypergonadotropic hypogonadism before hormonal treatment is selected, because...
Open access
Research Article10.9734/ajrre/2026/v9i1140
Linear growth in childhood is governed by a dense network of genetic, endocrine, and environmental signals, among which nutritional status occupies a central regulatory position. Body mass index, its standardised expression as a standard deviation score, height standard deviation...
Open access
Research Article10.9734/ajpr/2026/v16i7555
Severe childhood obesity has become one of the more pressing public health concerns of recent decades, affecting millions of children in both high-income and low- and middle-income settings. Its metabolic and cardiovascular consequences are well documented, but a growing body of...
Open access
Research Article10.9734/ajrid/2026/v17i7559
Background: Premature ovarian insufficiency is characterised by impaired ovarian function before 40 years of age and may present in adolescents and young women with delayed puberty, primary or secondary amenorrhoea, incomplete pubertal progression, hypo-oestrogenism, and elevated...
Open access
Research Article10.9734/ajrre/2026/v9i1136
Background: Female pubertal onset is a complex, multifactorial biological event with substantial global variation. Secular trends show progressive earlier thelarche and menarche across continents, yet biochemical thresholds for diagnosing pubertal onset and central precocious pub...
Open access
Research Article10.9734/ajrre/2026/v9i1132
Ashraf Soliman, Fawzia Alyafei, Nada Alaaraj, Noor Hamed, Ahmed Elawwa, Shayma Mohamed, Noora Alhumaidy, Khalid Siddiq & Mohamed Elkalaf·Asian Journal of Pediatric Research·2026
Background: Vitamin D is traditionally characterized as a nutrient essential for calcium homeostasis. However, emerging evidence suggests that the cutaneous CYP11A1-driven secosteroid pathway serves as a "chemical proxy" for sunlight, linking environmental UV radiation to the syn...
Open access
Research Article10.9734/ajpr/2026/v16i2522
Background and Significance: The eye is a target organ for almost every hormonal axis, and endocrine disease in childhood therefore carries ophthalmic consequences that are not simply earlier versions of adult disease. Ocular tissue in the growing child is still undergoing axial...
Open access
Research Article10.9734/or/2026/v21i4523
Vitamins are indispensable to ocular metabolism, yet the clinical meaning of a vitamin–eye association depends strongly on whether the individual is deficient, nutritionally replete, or receiving a pharmacological disease-specific formulation. This critical narrative review evalu...
Open access
Research Article10.9734/ajrrop/2026/v9i1166
The postnatal eye enlarges under tight optical control, coordinating corneal power, lens change and axial elongation so that the retinal image remains focused as the globe grows. Because this process unfolds during the same years in which the somatotropic axis drives somatic grow...
Open access
Research Article10.9734/ajrrop/2026/v9i1160