Aims: The use of medicinal plants in sub-Saharan Africa raises concerns regarding neurological safety. This study evaluated the effects of sub-chronic oral administration of ethanolic leaf extracts of Rauwolfia vomitoria (RV) and Gongronema latifolium (GL), singly and in combinat...
Open access
Research Article10.9734/ajorrin/2026/v9i1185
Aims: This study assessed histological parameter of the hippocampus using scopolamine-induced cognitive dysfunction rats following the administration of aqueous extract of Telfairia occidentalis seed. Materials and Methods: Thirty Wistar rats weighed between 180-200 g were random...
This study was designed to evaluate the anti-diarrhoeal activity of coconut water on castor oil induced-diarrhoea in adult albino Wistar rats. Sixty five adult male Albino Wistar rats weighing 150 – 250 g were used in this study. The study was carried out in three experiments (A,...
Open access
Research Article10.9734/BJMMR/2016/28378
The study evaluated the effect of combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on the pancreas of streptozotocin (STZ) induced diabetic Wistar rats. Thirty-two (32) albino rats were divided equally into 4 groups. Groups A and B which served as norm...
Open access
Research Article10.9734/BJMMR/2011/215
Eru Mba Eru, Theresa Ekpenyong Isamoh, Christabel Ojibima Francis, Williams A. Nnenna, E. Oku Michael, Onne Eru Mba, Eric Agim Agaba, Obinna Chukwuemeka Godfrey, Nwaguma Precious Chidinma & Anozeng O. Igiri·International Neuropsychiatric Disease Journal·2026
Aims: The study aimed to investigate the demographic distribution of patients diagnosed with dementia from the Federal Neuro-psychiatric Hospital (2011-2021), Calabar, Cross River State. Study design: The retrospective research design was adopted for the study. This was done to...
Open access
Research Article10.9734/indj/2026/v23i2550
Samson O. Paulinus, Eru M. Eru, Gabriel U. Udo-affah, Michael E. Oku, Ifiok Bassey, Kelechi C. Uruakpa, Nsikak M. Umoh, Michael Ajen, Sadeyeng E. Anani & Anozeng O. Igiri·Asian Journal of Research and Reports in Neurology·2024
Background: Oxidative stress augmented with progressive age, causes changes in mitochondrial DNA, mitochondrial disruption and more oxidative trouble. This process is facilitated in Alzheimer’s disease by the pathology of αβ amyloid and activated microglia. Objectives: The presen...
Eru, E.M, Theresa I. Ekpenyong, Cyril A. Agbor, Christie E. Fischer, Michael E. Oku, Samson O. Paulinus, Etim D. Isaiah, Kelechi C. Uruakpa, Williams A. Nnenna, Nsikak M. Umoh, Eric A. Agaba & Anozeng O. Igiri·International Neuropsychiatric Disease Journal·2025
Aim: the aim of this study was to elucidate the effect of alkaloid-rich fraction of Dacryodes edulis on body weight, blood glucose level and the microanatomy of the hippocampus of STZ-induced Diabetic Wistar rats. Methodology: 25 adult male Wistar rats were used for the experimen...
Open access
Research Article10.9734/indj/2025/v22i3477
Sadeyeng E. Anani, Michael E. Oku, Eru M. Eru, Kelechi C. Uruakpa, Ifiok F. Bassey, Gabriel U. Udo-affah, Paul A. Odey, Eric A. Agaba, Theresa E. Isamoh, Williams A. Nnenna, Nsikak N Umoh, Cletus U. Ajang & Anozeng O. Igiri·Asian Journal of Research and Reports in Neurology·2024
Introduction: Dacryodes edulis (African pear) is a medicinal plant known for its medicinal qualities. Its extracts are said to possess many health-promoting constituents such as antioxidants that have been used to treat many illnesses, including neurological disorders. Drug-induc...
Sadeyeng E. Anani, Williams A. Nnenna, Eric A. Agaba, Nsikak M. Umoh, Ifiok F. Bassey, Eru M. Eru, Michael E. Oku, Kelechi C. Uruakpa, Paul A. Odey, Theresa E. Isamoh, Cletus U. Ajang, Gideon Uzor, Gabriel U. Udo-affah & Anozeng O. Igiri·Asian Journal of Research and Reports in Neurology·2024
Introduction: The brain is an organ that is responsible for knowledge acquisition, cognition and control of body movements. Its normal functioning and structure can be affected by exposure to drugs of abuse (for example ketamine) which can cause disorder in the nervous system. Me...