Stabilized Arylzinc Iodides in Negishi Acylative Cross-Coupling: A Modular Synthesis of Chalcones
Michele Pierigé, Anna Iuliano, Gaetano Angelici & Gianluca Casotti · Organics · 2022
Stabilized arylzinc iodides, synthesized by direct insertion of zinc into the corresponding halides, were used as nucleophiles into an acylative Negishi coupling reaction to synthesize chalcones. The reaction conditions were optimized to afford optimal results on a model reaction...
Open access
Research Article
10.3390/org3020006