A Comparison of the Humoral Immune Response Induced by a Recombinant Human Protein in Wild Type Mice and in Transgenic Mice Expressing the Protein
Britta Granath, Jan Holgersson, Karin Cederbrant, Ann Lövgren & Nina Brenden · Journal of Pharmaceutical Research International · 2014
Aim: The aim of this work was to investigate the correlation between anti drug antibody (ADA) induction and how different manufacturing processes of biopharmaceuticals affect the immunogenicity of the protein. This was done by testing four different batches of the same recombinan...
Open access
Research Article
10.9734/BJPR/2014/10923