Ali B. Ishaque

The Effect of L-Buthionine Sulfoximine on the Toxicities and Interactions of As, Cd, Hg and Pb and their Composite Mixture on MCF 7 Cell Line

Charles K. Klutse, Egbe S. Egiebor, Isoken T. Aighewi & Ali B. Ishaque · Current Journal of Applied Science and Technology · 2014

The effect of intracellular level of GSH on the cytotoxicity and interaction of four environmentally relevant metals arsenic, cadmium, mercury and lead (As, Cd, Hg, and Pb) was investigated. L-Buthionine Sulfoximine (LBSO) was used to inhibit the intracellular level of GSH in MCF...

Open access Research Article 10.9734/BJAST/2015/13509

Oxidative Stress Pathway Mechanisms Induced by Four Individual Heavy Metals (As, Hg, Cd and Pb) and Their Quaternary on MCF-7 Breast Cancer Cells

Egbe Egiebor, Adam Tulu, Nadia Abou-Zeid, Ozuem F. Oseji & Ali B. Ishaque · Journal of Advances in Medicine and Medical Research · 2016

Cell death induced by the production of reactive oxygen species (ROS) has largely been associated with the activation of oxidative stress pathway; however, the direct mechanism(s) involved are unknown. This study evaluates the oxidative stress pathways by which four heavy metals...

Open access Research Article 10.9734/BJMMR/2016/27687