Thymic Atrophy during Infection as a Host Response to Avoid Tolerance to Persistent Pathogens
Leonardo Santos, Eugênia Terra-Granado, Luciana Conde, Ana Flávia Nardy & Alexandre Morrot · International Journal of TROPICAL DISEASE & Health · 2014
The immune system consists in part of a functionally competent T-cell repertoire that is reactive to foreign antigens but tolerant to self-antigens. The repertoire of T cells is primarily formed in the thymus through positive and negative selection of developing thymocytes that a...
Open access
Research Article
10.9734/IJTDH/2014/6481