Synthesis and Butyllithium-Induced Cyclisation of 2-Benzyloxyphenylphosphonamidates Giving 2,3-Dihydrobenzo[d][1,3]oxaphospholes
R. Alan Aitken, Khadija Ait Moulay, David B. Cordes, Ryan A. Inwood, Fraser G. Jamieson, Alexander J. B. Nelson & Aidan P. McKay · Organics · 2024
A series of fourteen O-ethyl-N-butylphenylphosphonamidates with benzyl ether substituents at the ortho position was prepared and fully characterised. Upon treatment with n-butyllithium in THF at RT, they underwent cyclisation in eight cases to give the novel 2,3-dihydrobenzo[d][1...
Open access
Research Article
10.3390/org5010002