Computer-Aided Design of Imidazo [4.5-c] Pyridin-4-one Derivatives as Antagonists of the Angiotensin II Type 1 (AT1) Receptor
Abel Landry Tebily, Akoun Abou, Issouf Soro, Abdoulaye Djandé, Niaré Adama & Megnassan Eugène · Journal of Pharmaceutical Research International · 2026
Over the past decade, drug resistance has emerged as a major challenge in the treatment of high blood pressure. This report evaluates new imidazo[4.5-c]pyridin-4-one compounds designed to inhibit the AT1 enzyme, and highlights their therapeutic potential, supported by favourable...
Open access
Research Article
10.9734/jpri/2026/v38i57837