Computer-assisted Design of Novel Polyketide Synthase 13 of Mycobacterium tuberculosis Inhibitors Using Molecular Modeling and Virtual Screening
Djako Akassa Marius Bernard, Melalie Keita, Yvon Bibila Mayaya Bisseyou, Akori Esmel & Eugene Megnassan · Journal of Pharmaceutical Research International · 2022
Aims: Polyketide synthase 13 (Pks13) is an essential enzyme in the synthesis of mycolic acids biosynthesis pathway of Mycobacterium tuberculosis (Mtb). Therefore, Pks13 is a promising drug target for tuberculosis treatment. Here we report the in silico design and evaluation of no...
Open access
Research Article
10.9734/jpri/2022/v34i567250