Background: Valproic acid (VPA) is an antiepileptic drug with a well-documented hepatotoxic effect among other several side effects. However, the effect of valproic acid administration on lipid profile and cardiovascular risk factors remains inconclusive and highly controversial....
Abiodun Olusoji Owoade, Adewale Adetutu, Olufemi Ogundeji Ogundipe, Akinade William Owoade & Esther Oluwakemi Kehinde·Asian Journal of Research in Biochemistry·2022
This study is aimed at investigating the effects of tamoxifen on lipid profile. In order to achieve this, tamoxifen was administered once daily intraperitoneally to the female rats at a dose of 2.07mg/kg body weight for 1 and 2 weeks, while a group of rats was allowed to recover...
Open access
Research Article10.9734/ajrb/2022/v10i330224
This study was carried out to compare the in-vitro antioxidant potentials, antidiabetic and phytochemical constituents of methanolic leaf extracts of Anthocleista djalonensis, Chrysophyllum albidium, Bauhinia thonningii, Daniellia oliveri, and Cola nitida. The results of this stu...
Open access
Research Article10.9734/jocamr/2021/v16i430302
Abiodun Olusoji Owoade, Adewale Adetutu, Olufemi Ogundeji Ogundipe & Akinade William Owoade·Asian Plant Research Journal·2021
The study was aimed to investigate the hypolipidemic potential of methanolic extract Rauvolfia vomitoria leaves in high cholesterol-fed rats. The preliminary study showed that R. vomitoria leaves were able to scavenge the 2,2-azino-bis (3-ethylbenzthiazoline-6-sufonic acid) (ABTS...
Open access
Research Article10.9734/aprj/2021/v8i430181
Abiodun Olusoji Owoade, Abdullahi Alausa, Adewale Adetutu, Akinade William Owoade, Olufemi Alamu Alamu & Olatundun Oludairo·Asian Journal of Research in Biochemistry·2021
This study evaluated the in- vitro antioxidant, phytochemical constituents and hepato-renal protective efficacy of Senna siamea methanolic extract in arsenic-induced oxidative stress. The results of this study show that S. siamea has strong antioxidant potentials against 2,2-Diph...
Open access
Research Article10.9734/ajrb/2021/v9i130194