Akanni E. Olufemi

African Polyherbal Formulation Possesses Chemopreventive and Chemotherapeutic Effects on Benzene- Induced Leukemia in Wistar Rats

Akanni E. Olufemi, Faremi Ayodeji, Akanni R. Adekemi, Bamisaye E. Oluseyi, Adewumi F. Ajoke, Agboola O. Aminat & Liasu O. Idris · Annual Research & Review in Biology · 2017

Background: Chemotherapy and radiotherapy are effective cancer treatment options but they are accompanied by serious side effects and complications such as systemic cytotoxicity, chemo- or radio-resistance. Therefore, more effective therapies are sorely needed. This study investi...

Open access Research Article 10.9734/ARRB/2017/34773

Kigelia africana Stem Bark, Fruit and Leaf Extracts Alleviate Benzene-induced Leukaemia in Rats

Akanni E. Olufemi, Olaniran I. Omotayo, Akinbo B. David, Iyiola Monjeed, Ogunlade Adebola, Sanni Bilikis & Adejumo Temitope · Journal of Pharmaceutical Research International · 2017

Aims: This study was aimed at evaluating the potential leukaemia chemotherapeutic activities of various extracts of Kigelia africana stem bark; fruit and leaf by using a benzene-induced model of leukaemia to validate its folkloric use. Evidences from African herbal medicine and t...

Open access Research Article 10.9734/JPRI/2017/34625

Tumour Suppressive and Organ Protective Effects of Aqueous Andrographis paniculata Leaves Extract on Benzene Induced Leukaemia Bearing Rats

Akanni E. Olufemi, O. R. Folarin & C. Igbeneghu · Annual Research & Review in Biology · 2013

Aims: To investigate and compare the protective and ameliorative role of aqueous leaf extract of Andrographis paniculata and standard drug 5-Fluorouracil on select organs of male Wistar rats exposed to benzene carcinogen. Study Design: Histological assessment of protective and am...

Open access Research Article 10.9734/ARRB/2014/6886