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Aïdote François

Publications (2)

DFT Study of Coordination of N-Monochlorosubstituation Derivatives of Biguanide

Aïdote François, Kuevi Urbain Amah, Kpotin Assongba Gaston & ATOHON Guy. Sylvain · International Research Journal of Pure and Applied Chemistry · 2024

Biguanides [HN=C(NR1R2)-NH-C(NR3R4)=NH] constitute an important family of molecules used as drugs in the treatment of diabetes. It is known that some transition metal complexes with given organic compounds deeply increase both therapeutic actions of the metal and the organic comp...

Open access Research Article 10.9734/irjpac/2024/v25i6888

DFT Study of the Coordination of N-monochlorosubstituted Derivatives of the N-deprotonated Tautomer of the Biguanide

Aïdote François, Kuevi Urbain Amah, Kpotin Assongba Gaston & Atohoun G. Sylvain · International Research Journal of Pure and Applied Chemistry · 2020

Biguanides [HN=C(NR1R2)-NH-C(NR3R4)=NH] constitute an important family of molecules used as drugs in the treatment of diabetes. When R1=R2=R3=R4=H the molecule is named simply “biguanide”. The five nitrogen atoms are potential coordination sites. Several experimental works publis...

Open access Research Article 10.9734/irjpac/2020/v21i230151