Chitosan Nanoparticles for Topical Co-administration of the Antioxidants Glutathione and Idebenone: Characterization and In vitro Release
Lucia Montenegro, Adriana Trapani, Paola Fini, Delia Mandracchia, Andrea Latrofa, Nicola Cioffi, Laura Chiarantini, Giusi Giada Picceri, Serena Brundu & Giovanni Puglisi · Journal of Pharmaceutical Research International · 2014
Aims: The aim of this study was to explore the potential of novel nanoparticles (NPs) intended for topical administration of the hydrophilic antioxidant Glutathione and the lipophilic Idebenone. Glutathione was introduced into the NPs using two approaches: i) covalently bonded to...
Open access
Research Article
10.9734/BJPR/2014/8641