Fungal infections have increased significantly in recent years and represent a major threat to human health. A large number of these infections are caused by the opportunistic pathogen Candida albicans. Lanosterol 14-alpha demethylase (CYP51), a critical enzyme in the cytochrome...
Open access
Research Article10.9734/irjpac/2025/v26i1899
Aims: This research aims to analyze the interactions within Epicatechin…Phenylalanine complexes and compare them to those in Epicatechin…Alanine complexes through theoretical chemistry calculations. Methodology: The interactions between Epicatechin and Phenylalanine, an amino aci...
Open access
Research Article10.9734/ajocs/2025/v15i1344
This work deals with the prediction of the antiproliferative activity of eighteen (18) substances derived from bis-5-arylidene rhodanine against human hepatoma tumor line (Huh-7D12). By applying the functional density theory (DFT) method to the B3LYP / 6-31G (d, p) level, theoret...
Open access
Research Article10.9734/ajocs/2019/v6i218993