A. Shashi

Molecular Mechanism of Changes in Gene Expression of Cytosolic Cu/Zn SOD, Lipid Peroxidation and Hepatic Function Impairments during Experimental Fluorosis

A. Shashi & Sukanya Thakur · Journal of Pharmaceutical Research International · 2021

Background: Long term intake of high amount of fluoride leads to fluorosis causing metabolic, functional and structural damages affecting many tissues and organs including dental and skeletal manifestations. The liver is the most susceptible organ to fluoride toxicity because of...

Open access Research Article 10.9734/jpri/2021/v33i46B32939

Therapeutic Effect of Curcumin on Scanning Electron Microscopy of Rat Adrenal Gland in Experimental Fluorosis

A. Shashi & Manisha Tikka · Journal of Pharmaceutical Research International · 2021

Aim: The present study was designed to investigate the therapeutic role of Curcumin against fluoride induced toxicity on adrenal gland of rats by using scanning electron microscopy (SEM). Methodology: Wistar albino rats were divided randomly into six groups The group I was admini...

Open access Research Article 10.9734/jpri/2021/v33i41A32333

SDS-PAGE and Densitometric Analysis of Myofibrillary Proteins: Actin and Myosin in Skeletal Muscle of Fluoride Intoxicated Rats

A. Shashi & Nidhi Rana · International Journal of TROPICAL DISEASE & Health · 2017

Aim: The present study was undertaken to evaluate the contractile proteins; Actin and Myosin in the skeletal muscle of rats exposed to three different concentrations of fluoride during 40 days of fluoride toxicity. Changes in muscle proteins of control and test rats have been exa...

Open access Research Article 10.9734/IJTDH/2017/36186