Application of Response Surface Methodology in Development and Optimization of Stability Indicating RP-HPLC Method for Determination of Tolvaptan in Bulk and Formulation
A. S. Sutar & C. S. Magdum · Journal of Pharmaceutical Research International · 2021
Design of Experiment assisted stability indicating RP-HPLC was developed and optimized using response surface methodology for determination of Tolvaptan. Mobile phase was developed and optimized using Design of Experiment with response surface methodology. Acetonitrile and phosp...
Open access
Research Article
10.9734/jpri/2021/v33i46A32850