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A. M. Umarudeen

Publications (5)

Substance Abuse among Residents of Gwagwalada Abuja, Nigeria

A. M. Umarudeen, O. N. Okoli, J. Mundi, E. Mitaire-Idonor, E. O. Moore & E. Adah · Archives of Current Research International · 2023

Aims: To determine the variety of psychoactive substances existing in Gwagwalada and the extent to which residents indulged in them. Study Design: A cross-sectional survey using questionnaires and audio interviews on eligible respondents. Place and Duration of Study: Gwagwalada,...

Open access Research Article 10.9734/acri/2023/v23i7586

Acute Toxicity and Anxiolytic Activity Screening of Hydroalcoholic Leaf Extracts of Bryophyllum pinnatum, Terminalia catappa and Tapinanthus dodoneifolius Growing on Terminalia catappa Tree in MIce

A. M. Umarudeen, M. G. Magaji, F. Khan & A. Abubakar · International Neuropsychiatric Disease Journal · 2023

Aims: Hydroalcoholic T. dodoneifolius, B.pinnatum and T. catappa leaf extracts were investigated for their acute toxicity and anxiolytic activities. Study Design: Acute toxicity (LD50) was determined using the limit dose acute and Anxiolytic activities were assessed by open-field...

Open access Research Article 10.9734/indj/2023/v19i3374

Appraising the Neurobehavioural Toxicity Potential of Aqueous Methanol Leaf Extract of Tapinanthus globiferus Growing on Azadirachta indica

A. M. Umarudeen & M. G. Magaji · International Neuropsychiatric Disease Journal · 2020

The high prevalence and disease burden of anxiety disorders against the paucity and liabilities of existing anxiolytics indicates a need for the discovery of additional/new anti-anxiety agents. However, it is necessary to further screen these new/putative anxiolytic compounds/ext...

Open access Research Article 10.9734/indj/2020/v14i230123

Anxiolytic Mechanism(S) and Corticosterone-Attenuating Effect of Hydroalcoholic Leaf Extract of Tapinanthus globiferus Mistletoe Growing on Azadirachta indica Tree

A. M. Umarudeen & M. G. Magaji · Journal of Complementary and Alternative Medical Research · 2020

Similar pharmacodynamic mechanism(s) often underlie drug actions and toxicities of anxiolytic agents and medicinal extracts. Extracts of Tapinanthus globiferus and related plant species have been reported with anxiolytic activities. But mechanistic evaluations on these plant extr...

Open access Research Article 10.9734/jocamr/2020/v10i130153

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

A. M. Umarudeen, M. G. Magaji, O. S. Bello, C. Aminu & M. I. Abdullahi · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The use of test batteries has been suggested as a means to enhance throughput, to broaden the spectrum of anxiety parameters detectable and to minimise the numbers of experimental animals required in behavioural studies. This study was undertaken to determine the sensitivity of t...

Open access Research Article 10.9734/jamps/2020/v22i430166