A. A. Kazi

Designing of some Novel Methyl 2-((4-(Benzamido)Phenyl)Sulfanyl)-1,2,3,4-tetrahydro-6-Methylpyrimidine-5-carboxylate Derivatives as Potential Glucokinase Activators through Molecular Docking

A. A. Kazi & V. A. Chatpalliwar · Journal of Pharmaceutical Research International · 2021

Aims: Glucokinase (GK) is a cytoplasmic enzyme that metabolizes the glucose to glucose- 6-phosphate and supports the adjusting of blood glucose levels within the normal range in humans. In pancreatic β-cells, it plays a leading role by governing the glucose-stimulated secretion o...

Open access Research Article 10.9734/jpri/2021/v33i44B32650

In-silico Inhibitory Potential of Triphala Constituents Against Cytochrome P450 2E1 for the Prevention of Thioacetamide-induced Hepatotoxicity

Aziz Unnisa, Sharuk L. Khan, Farooque A. H. Sheikh, Syed Mahefooz, A. A. Kazi, Falak A. Siddiqui, Nitin Gawai & Shweta G. Saboo · Journal of Pharmaceutical Research International · 2021

Background: Triphala, which is a combination of fruits of Terminalia chebula, Terminalia bellerica and Embilica officinalis generally recommended as herbal drug formulation in the Indian traditional medicine system. Study Design: To study the in-silico inhibitory potential of Tri...

Open access Research Article 10.9734/jpri/2021/v33i43A32499